本文選題：癲癇 + 癲癇發(fā)作��； 參考：《重慶醫(yī)科大學(xué)》2017年碩士論文

【摘要】：癲癇持續(xù)狀態(tài)(SE)神經(jīng)科常見(jiàn)的急危重癥,其病死率、致殘率高,迅速、有效地控制癲癇發(fā)作是挽救患者生命、改善預(yù)后的關(guān)鍵。目前臨床用于治療SE的傳統(tǒng)方案,盡管有60-70%的療效,但仍有30-40%的癲癇發(fā)作不能從目前的治療中獲益。鑒于癲癇持續(xù)狀態(tài)的病因多樣,發(fā)病機(jī)制復(fù)雜,聯(lián)合藥物治療因不同機(jī)制產(chǎn)生的協(xié)同作用,可能更有利于患者的治療,在缺乏實(shí)驗(yàn)及臨床證據(jù)證明單藥比聯(lián)合藥物治療更能改善SE患者預(yù)后情況下,探索SE的聯(lián)合應(yīng)用可能有其潛在的應(yīng)用價(jià)值。本綜述的目的是要總結(jié)近年來(lái)有關(guān)動(dòng)物實(shí)驗(yàn)及臨床實(shí)踐中聯(lián)合藥物治療SE的現(xiàn)狀,有助于研究者制定良好的前瞻性治療協(xié)議,尋求更好地治療SE的方案,以保證早期有效地應(yīng)用抗癲癇藥物終止SE。
[Abstract]:Epileptic status (SE) neurology is a common acute and critical disease. Its mortality and disability rate are high. It is the key to save life and improve prognosis to control seizures quickly and effectively. Despite 60-70% curative effect, 30-40% of epileptic seizures do not benefit from the current treatment. Since the etiology of epileptic status is diverse and the pathogenesis is complex, the synergistic effect of combined drug therapy due to different mechanisms may be more beneficial to the treatment of patients. In the absence of experimental and clinical evidence to prove that single drug therapy can improve the prognosis of patients with SE, exploring the combined use of SE may have its potential application value. The purpose of this review is to summarize the current situation of combined drug therapy in animal experiments and clinical practice in recent years, and to help researchers to formulate a good prospective treatment protocol and to seek a better regimen for the treatment of SE. In order to ensure the early and effective use of antiepileptic drugs to terminate Se.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R742.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

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本文編號(hào)：2061769