益氣養(yǎng)陰活血法對2型糖尿病腦梗死患者糖代謝指標(biāo)、血管內(nèi)皮功能及預(yù)后的影響
發(fā)布時間:2018-06-23 17:42
本文選題:型糖尿病 + 腦梗死; 參考:《中國地方病防治雜志》2017年02期
【摘要】:目的探討益氣養(yǎng)陰活血法對2型糖尿病腦梗死患者糖代謝指標(biāo)、血管內(nèi)皮功能及預(yù)后的影響。方法選擇2014年12月至2015年12月本院接診的100例2型糖尿病合并腦梗死的患者,通過隨機數(shù)表法分為觀察組和對照組,各50例。給予對照組常規(guī)的治療方式,觀察組在對照組的基礎(chǔ)上加用益氣養(yǎng)陰活血法。觀察兩組治療前后糖代謝指標(biāo)、血管內(nèi)皮功能、神經(jīng)缺損評分、日常生活能力評分的變化,并對治療后臨床療效比較。結(jié)果治療后,觀察組空腹血糖(FBG)、糖化血紅蛋白(HbAlc)水平均低于對照組[(7.05±1.20)mmol/L比(8.43±1.56)mmol/L,(10.27±1.01)%比(11.68±2.54)%],血管內(nèi)皮細(xì)胞生長因子(VEGF)水平高于對照組[(184.24±17.91)ng/L比(153.23±15.86)ng/L],神經(jīng)功能缺損評分低于對照組,日常生活能力評分高于對照組[(8.34±1.42)比(15.76±3.18),(85.46±7.81)比(73.13±6.43)],治療后總有效率比對照組高[82.0%(41/50)比98.0%(49/50)],差異均具有統(tǒng)計學(xué)意義(P0.05)。結(jié)論在2型糖尿病腦梗死患者中使用益氣養(yǎng)陰活血法可有效改善患者血糖水平、血管內(nèi)皮功能及日常生活能力,提高預(yù)后,效果顯著,值得在臨床上應(yīng)用推廣。
[Abstract]:Objective to investigate the effects of supplementing qi and nourishing yin and activating blood circulation on glucose metabolism, vascular endothelial function and prognosis in type 2 diabetic patients with cerebral infarction. Methods 100 patients with type 2 diabetes complicated with cerebral infarction from December 2014 to December 2015 were randomly divided into observation group (n = 50) and control group (n = 50). The control group was given routine treatment, and the observation group was treated with the method of nourishing qi, nourishing yin and activating blood circulation on the basis of control group. The changes of glucose metabolism index, vascular endothelial function, nerve defect score and activity of daily living score were observed before and after treatment, and the clinical efficacy was compared. Results after treatment, the levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbAlc) in the observation group were lower than those in the control group [(7.05 鹵1.20) mmol / L, (8.43 鹵1.56) mmol / L, (10.27 鹵1.01)% vs (11.68 鹵2.54)%], and the levels of vascular endothelial growth factor were higher than those in the control group [(184.24 鹵17.91) ng / L vs (153.23 鹵15.86) ng / L]. The score of ADL was higher than that of the control group [(8.34 鹵1.42) vs (15.76 鹵3.18), () 85.46 鹵7.81], and the total effective rate after treatment was higher than that of the control group [82.0% (41 / 50) vs 98.0% (49 / 50)]. The difference was statistically significant (P0.05). Conclusion the method of nourishing qi, nourishing yin and activating blood circulation can effectively improve the blood sugar level, vascular endothelial function and daily living ability in patients with type 2 diabetes mellitus cerebral infarction, and improve the prognosis. It is worth popularizing in clinic.
【作者單位】: 沂南縣人民醫(yī)院;
【基金】:山東省中醫(yī)藥科技發(fā)展計劃項目(2013104)
【分類號】:R587.2;R743.33
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1 李業(yè)輝;宋恩峰;;中西醫(yī)結(jié)合治療老年2型糖尿病臨床觀察[J];湖北中醫(yī)藥大學(xué)學(xué)報;2014年01期
,本文編號:2057894
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