本文選題：癲癇 + 抑郁障礙�。� 參考：《南昌大學》2014年碩士論文

【摘要】：目的：分析癲癇患者焦慮、抑郁障礙的發(fā)生率及影響因素；探討癲癇與焦慮及抑郁障礙共病的可能發(fā)病機制，為癲癇的臨床治療提供理論依據(jù)。 方法：選擇2012年5月~2013年12月在南昌大學二附院神經(jīng)內(nèi)科門診就診和病房住院的（經(jīng)知情同意）癲癇患者,嚴格按照入選標準納入，采用漢密頓抑郁量表及漢密頓焦慮量表對患者進行測查，用ⅹ2檢驗及Logistic多元回歸分析對相關(guān)因素進行分析。 結(jié)果：癲癇患者抑郁障礙發(fā)生率為42.8%，焦慮障礙的發(fā)生率為67.9%。單因素卡方檢驗及多因素Logistic回歸分析結(jié)果提示：癲癇患者焦慮、抑郁障礙的發(fā)生與癲癇的發(fā)作類型（OR2.1, P0.820）(OR0.85, P0.098)、發(fā)作頻率（OR0.34,P0）(OR2.60, P0.011)、病變部位（OR2.08, P0.05）(OR2.10, P0.680)、及文化程度（OR0.64, P0.827）（OR0.70，，P0.593）等因素有關(guān)；用藥數(shù)量(OR1.45, P0.241)是癲癇患者焦慮障礙的影響因素之一,病程(OR0.39, P0.060)是癲癇患者抑郁障礙的影響因素之一;而居住地區(qū)（OR0.41，P0.246）可能與癲癇伴發(fā)抑郁有關(guān)。 結(jié)論：癲癇患者伴發(fā)抑郁、焦慮障礙的主要影響因素是發(fā)作頻率，癲癇患者伴發(fā)抑郁障礙可能的相關(guān)因素之一是居住地區(qū)。
[Abstract]:Objective: to analyze the incidence and influencing factors of anxiety and depressive disorder in epileptic patients, and to explore the possible pathogenesis of epilepsy with anxiety and depressive disorder in order to provide theoretical basis for the clinical treatment of epilepsy. Methods: patients with epilepsy were selected from May 2012 to December 2013 in the Department of Neurology, second affiliated Hospital, Nanchang University, and hospitalized (with informed consent). Hamilton Depression scale and Hamilton anxiety scale were used to test the patients, and the related factors were analyzed by x 2 test and Logistic multiple regression analysis. Results: the incidence of depressive disorder and anxiety disorder in epileptic patients was 42.8 and 67.9 respectively. The results of univariate chi-square test and multivariate logistic regression analysis showed that the occurrence of anxiety and depression in epileptic patients was related to the type of seizure, such as OR 2.1, P 0.820, OR 0.85, P 0.098, OR 0.34, P 0.011, the site of disease was OR2.08, P0.05OR2.10, P0.680, and the cultural level of OR0.64, P0.827O0.700.593). OR1.45, P0.241) is one of the influencing factors of anxiety disorder in epileptic patients, and the course of disease OR0.39, P0.060) is one of the influencing factors of depressive disorder in epileptic patients, while OR0.41P0.246) may be related to the depression associated with epilepsy. Conclusion: the frequency of seizure is the main influencing factor of depression and anxiety disorder in epileptic patients, and one of the possible related factors of depressive disorder in epileptic patients is residential area.
【學位授予單位】：南昌大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R742.1

【引證文獻】

相關(guān)期刊論文 前1條

1 陳艷麗;蘇偉兵;;癲癇病人的綜合護理[J];大家健康(學術(shù)版);2015年20期

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