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鞍區(qū)腦膜瘤的臨床特征及手術(shù)治療策略

發(fā)布時(shí)間:2018-06-13 13:30

  本文選題:鞍區(qū)腦膜瘤 + 臨床特征; 參考:《重慶醫(yī)科大學(xué)》2014年碩士論文


【摘要】:目的:探討鞍區(qū)腦膜瘤的臨床特征及手術(shù)治療策略。 方法:回顧性分析我院經(jīng)手術(shù)治療鞍區(qū)腦膜瘤49例臨床資料,比較鞍上型與鞍旁型腦膜瘤的臨床特征,對(duì)比單側(cè)額下入路與翼點(diǎn)入路的差異,總結(jié)鞍區(qū)腦膜瘤手術(shù)治療策略。 結(jié)果:鞍上型21例,鞍旁型28例,鞍上型腦膜瘤對(duì)視力、視野的影響及對(duì)垂體、視神經(jīng)壓迫較鞍旁型更常見(P 0.05)。49例鞍區(qū)腦膜瘤,按simpson分級(jí)標(biāo)準(zhǔn)全切33例,次全切14例,部分切除2例,全切率為67.3%。單側(cè)額下入路與翼點(diǎn)入路相比,術(shù)中出血量、手術(shù)時(shí)間及術(shù)后住院時(shí)間均無差異(P0.05)。 結(jié)論:鞍上型與鞍旁型腦膜瘤的臨床特點(diǎn)具有差異,前者對(duì)視力、視野的影響及對(duì)垂體、視神經(jīng)壓迫更常見。在保留患者神經(jīng)功能及生活質(zhì)量的基礎(chǔ)上,,最大程度切除腫瘤是主要目的,單側(cè)額下入路及翼點(diǎn)入路均能使鞍區(qū)腫瘤獲得良好暴露,對(duì)比術(shù)中出血量、手術(shù)時(shí)間及住院時(shí)間無明顯差異。
[Abstract]:Objective: to investigate the clinical features and surgical treatment of Sellar meningioma. Methods: the clinical data of 49 patients with Sellar meningioma were analyzed retrospectively. The clinical characteristics of suprasellar meningioma and parasellar meningioma were compared, the differences between unilateral subfrontal approach and pterional approach were compared, and the surgical treatment strategies of Sellar meningioma were summarized. Results: there were 21 cases of suprasellar type, 28 cases of parasellar type, the effect of suprasellar meningioma on visual acuity, visual field and pituitary gland. The optic nerve compression was more common than parasellar type in 49 cases of Sellar meningioma. According to simpson classification standard, 33 cases had total resection and 14 cases had subtotal resection. Partial resection was performed in 2 cases, total resection rate was 67.3%. There was no significant difference in blood loss, operation time and postoperative hospitalization time between unilateral subfrontal approach and pterional approach. Conclusion: the clinical features of suprasellar meningioma and parasellar meningioma are different. The influence of the former on visual acuity, visual field, pituitary gland and optic nerve compression is more common. On the basis of preserving the nerve function and quality of life of the patients, the main objective was to remove the tumor to the maximum extent. Both unilateral subfrontal approach and pterional approach could expose the Sellar region tumor well and compare the amount of intraoperative bleeding. There was no significant difference in operation time and hospital stay.
【學(xué)位授予單位】:重慶醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R739.45;R730.56

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