腦梗死出血轉(zhuǎn)化后繼續(xù)阿司匹林抗血小板聚集治療的效果
發(fā)布時(shí)間:2018-05-30 11:19
本文選題:腦梗死 + 出血轉(zhuǎn)化��; 參考:《臨床醫(yī)學(xué)工程》2016年12期
【摘要】:目的探討腦梗死出血轉(zhuǎn)化后繼續(xù)服用阿司匹林臨床抗血小板聚集的效果。方法選取我院2013年1月至2015年12月期間120例急性腦梗死入院治療出現(xiàn)出血癥狀的患者,按雙盲法隨機(jī)分為實(shí)驗(yàn)組60例、對(duì)照組60例。在給予相應(yīng)對(duì)癥治療的同時(shí),實(shí)驗(yàn)組繼續(xù)使用阿司匹林,對(duì)照組停止服用抗血小板聚集藥物并在出血穩(wěn)定后繼續(xù)啟用。結(jié)果治療后,實(shí)驗(yàn)組較對(duì)照組纖維蛋白水平指標(biāo)恢復(fù)好(P0.05),經(jīng)頭顱CT檢查顯示兩組的腦出血量均未見(jiàn)明顯增加(P0.05)。治療前和治療3個(gè)月后,兩組神經(jīng)損傷程度比較無(wú)統(tǒng)計(jì)學(xué)差異(P0.05);治療1個(gè)月后,實(shí)驗(yàn)組的神經(jīng)損傷程度評(píng)分顯著低于對(duì)照組(P0.05)。結(jié)論對(duì)腦梗死出血轉(zhuǎn)化患者,臨床發(fā)現(xiàn)出血后繼續(xù)使用阿司匹林抗血小板治療,有利于神經(jīng)功能恢復(fù)和血液流變學(xué)指標(biāo)恢復(fù)。
[Abstract]:Objective to investigate the effect of aspirin on platelet aggregation after cerebral infarction. Methods from January 2013 to December 2015, 120 patients with acute cerebral infarction were randomly divided into experimental group (n = 60) and control group (n = 60). While the corresponding symptomatic treatment was given, the experimental group continued to use aspirin, while the control group stopped taking the antiplatelet aggregation drug and continued to use it after the bleeding stabilized. Results after treatment, the fibrin level of the experimental group recovered better than that of the control group (P0.05A), and the cerebral hemorrhage volume of the two groups was not significantly increased by CT examination. There was no significant difference in the degree of nerve injury between the two groups before and after 3 months of treatment, but after one month of treatment, the score of nerve injury in the experimental group was significantly lower than that in the control group (P 0.05). Conclusion Aspirin antiplatelet therapy is beneficial to the recovery of nerve function and hemorheology in patients with cerebral infarction.
【作者單位】: 廣東省高州市人民醫(yī)院;
【分類號(hào)】:R743.33
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本文編號(hào):1955116
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