本文選題：腦梗死 + 省風(fēng)導(dǎo)痰湯��； 參考：《廣州中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的：觀察省風(fēng)導(dǎo)痰湯治療急性腦梗死的臨床療效；探究患者入院時(shí)的內(nèi)皮祖細(xì)胞水平、頸動(dòng)脈形態(tài)特征與療效的相關(guān)性。方法：60例病例來源于江門市新會(huì)中醫(yī)院內(nèi)二科2015年7月至2016年2月期間收治中風(fēng)(痰證)的患者。全數(shù)病例均與《中國(guó)急性缺血性腦卒中診治指南2010》及《中風(fēng)病診斷與療效評(píng)定標(biāo)準(zhǔn)試行(1995)》的診斷標(biāo)準(zhǔn)切合。隨機(jī)分為兩組,兩組年齡、性別差異無統(tǒng)計(jì)學(xué)意義(P0.05)。兩組均給以西醫(yī)常規(guī)基礎(chǔ)治療,觀察組在基礎(chǔ)治療方案之上加用省風(fēng)導(dǎo)痰湯加減,復(fù)煎,一天兩次,每次100m1,口服。觀察指標(biāo)：美國(guó)國(guó)立衛(wèi)生研究院卒中量表(NIHSS評(píng)分),在入院前、治療后第7天、第14天、第21天及第28天時(shí)評(píng)估;頸動(dòng)脈狹窄程度及循環(huán)內(nèi)皮祖細(xì)胞水平,在入院前評(píng)估。全部資料輸入SPSS 18.0軟件進(jìn)行統(tǒng)計(jì)分析,P0.05為顯著性。結(jié)果：共選60例患者,隨機(jī)分入兩組。NIHSS評(píng)分：總體而言,觀察組及對(duì)照組受試者的NIHSS評(píng)分在不同的治療方案、不同治療時(shí)程上變化的趨勢(shì)呈顯著的統(tǒng)計(jì)學(xué)差異(P0.01),觀察組療效明顯優(yōu)于對(duì)照組。分組比較,治療前兩組差異無統(tǒng)計(jì)學(xué)意義(P0.05)；治療后第7天、第14天,兩組差異無統(tǒng)計(jì)學(xué)意義；第21天和第28天,兩組差異有統(tǒng)計(jì)學(xué)意義,觀察組療效均優(yōu)于對(duì)照組(P0.05),第28天差異顯著(P0.01)�？祻�(fù)程度與頸動(dòng)脈狹窄程度的相關(guān)性分析：觀察組的康復(fù)程度與治療前頸動(dòng)脈狹窄程度具有顯著的相關(guān)性(P0.05),且呈正相關(guān)；對(duì)照組的康復(fù)程度與治療前頸動(dòng)脈硬化程度相關(guān)性不明顯�？祻�(fù)程度與內(nèi)皮祖細(xì)胞水平的相關(guān)性分析：觀察組的康復(fù)程度與治療前內(nèi)皮祖細(xì)胞水平相關(guān)性不明顯；對(duì)照組的康復(fù)程度與治療前頸動(dòng)脈硬化程度具有顯著的相關(guān)性(P0.05),且呈正相關(guān)。結(jié)論：臨床研究的結(jié)果顯示,相對(duì)于單純西醫(yī)治療痰證中風(fēng)的患者,聯(lián)合使用省風(fēng)導(dǎo)痰湯加減在改善臨床癥狀及預(yù)后方面療效更佳。
[Abstract]:Objective: to observe the clinical effect of provincial wind guide phlegm decoction in treating acute cerebral infarction and to explore the correlation of endothelial progenitor cells (EPCs), carotid artery morphology and curative effect in patients with acute cerebral infarction. Methods 60 cases of stroke (phlegm syndrome) were treated from July 2015 to February 2016 in two departments of Xinhui traditional Chinese Medicine Hospital in Jiangmen City. All the cases were in accordance with the diagnostic criteria of the guidelines for the diagnosis and treatment of Acute Ischemic Stroke in China (2010) and the criteria for the diagnosis and Evaluation of Stroke (1995). They were randomly divided into two groups. There was no significant difference in age and sex between the two groups (P 0.05). Both groups were given routine western medicine basic treatment, observation group on the basis of the basic treatment of the combined use of Fengguo phlegm decoction, twice a day, 100 ml, oral. Outcome measures: NIHSS scores were evaluated before admission, 7 days, 14 days, 21 days and 28 days after treatment, and carotid stenosis and circulating endothelial progenitor cell levels were evaluated before admission. All data were inputted into SPSS 18.0 software for statistical analysis. Results: a total of 60 patients were randomly divided into two groups. NIHSS scores: overall, the NIHSS scores of the observation group and the control group were in different treatment plans. There was significant statistical difference in the trend of changes in different treatment stages (P 0.01), and the curative effect of the observation group was significantly better than that of the control group. There was no significant difference between the two groups before treatment (P 0.05); on day 7 and day 14 after treatment, there was no significant difference between the two groups; on day 21 and day 28, the difference between the two groups was statistically significant. The curative effect of the observation group was better than that of the control group (P 0.05), and the difference on the 28th day was significant (P 0.01). The correlation between the degree of rehabilitation and the degree of carotid artery stenosis: in the observation group, there was a significant correlation between the degree of rehabilitation and the degree of carotid artery stenosis before treatment, and there was a positive correlation between the degree of rehabilitation and the degree of carotid artery stenosis. There was no significant correlation between the degree of rehabilitation and the degree of carotid atherosclerosis before treatment in the control group. Correlation analysis between rehabilitation degree and endothelial progenitor cell level: there was no significant correlation between the rehabilitation degree of observation group and the level of endothelial progenitor cell before treatment. There was a significant correlation between the degree of rehabilitation and the degree of carotid atherosclerosis before treatment in the control group, and there was a positive correlation between the degree of rehabilitation and the degree of carotid arteriosclerosis before treatment. Conclusion: the results of clinical study showed that compared with the treatment of phlegm syndrome apoplexy patients with phlegm syndrome by western medicine alone, combined use of Fengguo phlegm decoction was better in improving clinical symptoms and prognosis.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R743.3

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 黃明;梁華庚;喻水平;;導(dǎo)痰湯加減治療急性缺血性腦梗死臨床療效觀察[J];醫(yī)學(xué)理論與實(shí)踐;2013年12期

2 于福江;;導(dǎo)痰湯古今異考[J];中醫(yī)藥學(xué)報(bào);1987年03期

3 鄧成明,趙蘇萍;談導(dǎo)痰湯在婦科臨床的運(yùn)用[J];貴陽中醫(yī)學(xué)院學(xué)報(bào);1997年03期

4 馬惠敏;運(yùn)用導(dǎo)痰湯的點(diǎn)滴體會(huì)[J];湖北中醫(yī)雜志;1997年06期

5 周京述;;用補(bǔ)中導(dǎo)痰湯減肥的經(jīng)驗(yàn)[J];成都中醫(yī)學(xué)院學(xué)報(bào);1988年01期

6 邱志濟(jì);導(dǎo)痰湯治頑痰痼疾舉隅[J];四川中醫(yī);1996年01期

7 張常彩;杜昌立;陳龍?chǎng)?;導(dǎo)痰湯治療椎基底動(dòng)脈供血不足106例臨床觀察[J];實(shí)用中西醫(yī)結(jié)合臨床;2007年05期

8 王穎;;導(dǎo)痰湯加減臨床應(yīng)用舉隅[J];實(shí)用中醫(yī)內(nèi)科雜志;2011年10期

9 曾熙光;導(dǎo)痰湯加味治療手臂痛[J];四川中醫(yī);1987年02期

10 沈企華;導(dǎo)痰湯臨床應(yīng)用體會(huì)[J];浙江中醫(yī)學(xué)院學(xué)報(bào);1987年05期

相關(guān)會(huì)議論文 前1條

1 丁彩飛;王晨曄;鄭若Y，

本文編號(hào)：1941873