本文選題：腦干聽覺誘發(fā)電位 + 后循環(huán)�。� 參考：《蚌埠醫(yī)學(xué)院》2017年碩士論文

【摘要】：目的:分析腦干聽覺誘發(fā)電位在腦干梗死早期有無(wú)異常變化,以及對(duì)腦干梗死發(fā)生進(jìn)展有無(wú)早期預(yù)警價(jià)值。方法:對(duì)發(fā)病24h內(nèi)入院經(jīng)頭顱MRI確診為腦干梗死的患者,在入院時(shí)行腦干聽覺誘發(fā)電位檢查(BAEP),并在入院時(shí)及在病程的48h對(duì)患者進(jìn)行美國(guó)國(guó)立衛(wèi)生研究所腦卒中量表(NIHSS)評(píng)分,根據(jù)兩次NIHSS評(píng)分結(jié)果,且符合入選及排除標(biāo)準(zhǔn),分為腦干缺血性進(jìn)展性卒中組(SIP組)與腦干缺血性非進(jìn)展性卒中組(對(duì)照組),比較兩組患者剛?cè)朐簳r(shí)的BAEP檢查結(jié)果,以I、Ⅲ、V各波峰潛伏期(PL)和I～Ⅲ、Ⅲ～V、I～V各峰間潛伏期(IPL)為觀察指標(biāo),并對(duì)兩組患者BAEP檢查結(jié)果進(jìn)行對(duì)比分析。結(jié)果:1、本研究共完成36例,SIP組18例,其中男性患者10例,女性患者8例,年齡49～82歲,平均年齡72.50±8.91歲;對(duì)照組18例,其中男性患者9例,女性患者9例,年齡47～85歲,平均年齡73.06±10.11歲。兩組研究對(duì)象性別、年齡、高血壓、糖尿病等一般資料均具有可比性,即差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。2、對(duì)照組BAEP總異常率為83.33%,單側(cè)異常率22.22%,雙側(cè)異常率61.11%,主要異常表現(xiàn)是雙側(cè)Ⅲ、V波的PL及Ⅲ～V波的IPL延長(zhǎng),SIP組BAEP總異常率為88.89%,單側(cè)異常率22.22%,雙側(cè)異常率66.67%,主要異常表現(xiàn)是雙側(cè)Ⅲ、V波的PL及Ⅲ～V波的IPL延長(zhǎng);兩組BAEP比較發(fā)現(xiàn),其總異常率、單側(cè)異常率、雙側(cè)異常率及I、Ⅲ、V波的PL,I-Ⅲ、I-V的IPL異常率差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),但SIP組Ⅲ-V波IPL的異常率較對(duì)照組明顯升高以及Ⅲ-V的IPL值較對(duì)照組明顯延長(zhǎng)(即差異具有統(tǒng)計(jì)學(xué)意義,P0.05)。結(jié)論:1、BAEP可以作為腦干梗死早期診斷的輔助檢查,且異常表現(xiàn)主要是雙側(cè)Ⅲ、V波的PL及Ⅲ～V波的IPL延長(zhǎng);2、本研究初步探討了BAEP與腦干梗死發(fā)生進(jìn)展的關(guān)系,發(fā)現(xiàn)腦干梗死早期BAEPⅢ～V波的IPL值延長(zhǎng)顯著者可能容易發(fā)生進(jìn)展,即腦干梗死早期BAEPⅢ～V波的IPL值對(duì)腦干梗死發(fā)生進(jìn)展可能有早期預(yù)警價(jià)值。但由于本研究樣本量較小,不具備行多因素回歸分析的條件,即不能排除其他潛在的危險(xiǎn)因素的影響,今后我們將擴(kuò)大樣本量進(jìn)一步研究。
[Abstract]:Objective: to analyze the abnormal changes of brainstem auditory evoked potential (BAEP) in the early stage of brain-stem infarction and its early warning value. Methods: brainstem auditory evoked potential (BAEPP) examination was performed in patients with brainstem infarction diagnosed by MRI within 24 hours after the onset of the disease. The stroke scale (NIHSS) of the National Institutes of Health (NIH) was evaluated on admission and 48 hours after the onset of the disease. According to the results of two NIHSS scores, and according to the criteria of admission and exclusion, they were divided into two groups: brainstem ischemic progressive stroke group and brainstem ischemic non-progressive stroke group (control group). The results of BAEP examination at admission were compared between the two groups. I, 鈪，

本文編號(hào)：1878143