本文選題：帕金森病 + 疲勞�。� 參考：《東南大學(xué)學(xué)報(醫(yī)學(xué)版)》2017年06期

【摘要】：目的:研究帕金森病(PD)患者伴發(fā)疲勞的情況及其相關(guān)因素。方法:以97例PD患者為研究對象,應(yīng)用疲勞嚴重程度量表對患者進行疲勞評估。記錄所有患者統(tǒng)一帕金森病量表(UPDRS)評分,Hoehn-Yahr(H-Y)分期,Beck焦慮量表(BAI)、Beck抑郁量表(BDI)、帕金森病睡眠量表(PDSS)、39項PD問卷(PDQ-39)評分及左旋多巴等效劑量(LED),比較疲勞組和非疲勞組之間是否存在差異。結(jié)果:97例患者中,63例(63.9%)存在疲勞。UPDRS評分,H-Y分期,BAI、BDI、PDSS、PDQ-39評分及LED與疲勞相關(guān)。Logistic回歸分析顯示,BDI和PDSS評分是疲勞的獨立危險因素。結(jié)論:PD患者疲勞的發(fā)生率高,抑郁和睡眠障礙是影響疲勞的主要因素,嚴重影響患者的生活質(zhì)量。
[Abstract]:Objective: to study the prevalence of fatigue in patients with Parkinson's disease (PD) and its related factors. Methods: 97 PD patients were studied. Fatigue severity scale was used to evaluate fatigue. All the patients were assessed with the Unified Parkinson's Disease scale (UPDRS) and the Beck anxiety scale (Beck anxiety scale), the Beck Depression scale (BAIK) and the PDQ-39 (PDQ-39) score and the equivalent dose of levodopa. The differences between the fatigue group and the non-fatigue group were compared between the fatigue group and the non-fatigue group. Results among 97 patients, 63 cases (63.9%) had fatigue. UPDRS score and H-Y stage. LED and fatigue related. Logistic regression analysis showed that BDI and PDSS scores were independent risk factors of fatigue. Conclusion the incidence of fatigue is high in the patients with 1% PD. Depression and sleep disorder are the main factors affecting fatigue and seriously affect the quality of life of the patients.
【作者單位】： 南通大學(xué)附屬醫(yī)院神經(jīng)內(nèi)科;
【分類號】：R742.5
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本文編號：1856775