本文選題：腦梗塞 + 丹紅注射液��； 參考：《西部醫(yī)學》2016年02期

【摘要】：目的探討丹紅注射液聯(lián)合奧拉西坦治療腦梗塞的療效;方法將我院收治的76例腦梗塞患者隨機分為對照組與治療組,分別以丹紅注射液(對照組)及丹紅注射液聯(lián)合奧拉西坦(治療組)進行靜脈滴注,對比兩組的臨床療效及治療前后的神經(jīng)功能缺損程度與血液流變學指標。結果治療組的有效率97.3%,對照組有效率為92.2%,但未見顯著差異。而治療組的治愈率、顯效率均顯著高于對照組(P0.05);治療3個月后,治療組的NIM評分與治療前對比有了顯著下降(P0.05);而對照組雖有下降,但差異無統(tǒng)計學意義(P0.05),其評分高于治療組(P0.05);治療后,所有患者的全血漿粘度、血小板聚集率、血栓形成系數(shù)及心排血指數(shù)均相對治療前有了顯著下降(P0.05),但治療組的下降程度更低于對照組(P0.05),并且對于兩組患者治療后腦部血液動力學指標如:平均血流量、平均血流速度、腦血管特性阻抗均在治療后明顯上升,差異有統(tǒng)計學意義(P0.05);腦血管外周阻力變化顯著,差異有統(tǒng)計學意義(P0.01)。結論丹紅注射液聯(lián)合奧拉西坦可促進腦梗塞的臨床治療效果,促進神經(jīng)功能的恢復,有效改善患者預后。
[Abstract]:Objective to investigate the therapeutic effect of Danhong injection combined with oxiracetam on cerebral infarction methods 76 patients with cerebral infarction in our hospital were randomly divided into control group and treatment group. Danhong injection (control group) and Danhong injection combined with oxiracetam (treatment group) were given intravenously respectively. The clinical efficacy, the degree of nerve function defect and hemorheology were compared between the two groups before and after treatment. Results the effective rate of the treatment group was 97.3%, while the control group was 92.2%, but there was no significant difference. After 3 months of treatment, the NIM score of the treatment group was significantly lower than that of the pre-treatment group (P 0.05), while the control group had a decrease. But the difference was not statistically significant (P 0.05), and its score was higher than that in the treatment group (P 0.05). After treatment, the whole plasma viscosity and platelet aggregation rate of all patients were higher than those of the treatment group. The thrombus formation coefficient and cardiac blood excretion index were significantly decreased compared with those before treatment, but the degree of decrease in the treatment group was lower than that in the control group (P 0.05), and the cerebral hemodynamic indexes such as mean blood flow, mean blood flow velocity after treatment in both groups were lower than those in the control group. The characteristic impedance of cerebrovascular increased significantly after treatment, the difference was statistically significant (P 0.05), and the change of peripheral resistance was significant (P 0.01). Conclusion Danhong injection combined with olaxetam can promote the clinical effect of cerebral infarction, promote the recovery of nerve function and improve the prognosis of the patients.
【作者單位】： 武漢市東西湖區(qū)人民醫(yī)院神經(jīng)內(nèi)科;珠海市第二人民醫(yī)院檢驗科;
【基金】：湖北省科技支撐項目(hb2012D136001342)
【分類號】：R743.3
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本文編號：1821132