本文選題：尤瑞克林 + 降纖酶�。� 參考：《中國地方病防治雜志》2017年01期

【摘要】：目的探討尤瑞克林聯(lián)合降纖酶對急性腦梗塞患者神經(jīng)功能缺損及血漿纖維蛋白原的影響。方法 67例急性腦梗塞患者隨機分為對照組33例,觀察組34例,對照組予尤瑞克林治療,觀察組予尤瑞克林聯(lián)合降纖酶治療,比較兩組治療前后神經(jīng)功能缺損(NIHSS)評分、血漿纖維蛋白原水平,統(tǒng)計臨床療效及不良反應(yīng)發(fā)生率。結(jié)果觀察組總有效率94.12%高于對照組72.73%(P0.05);治療后1、2周、1個月觀察組NIHSS評分及血漿纖維蛋白原水平均低于對照組(P0.05);兩組不良反應(yīng)發(fā)生率差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論尤瑞克林聯(lián)合降纖酶治療急性腦梗塞患者療效顯著,可有效改善患者血漿纖維蛋白原水平及神經(jīng)功能缺損程度,安全性高。
[Abstract]:Objective to investigate the effects of eurexine combined with defibrase on neurologic impairment and plasma fibrinogen in patients with acute cerebral infarction. Methods Sixty-seven patients with acute cerebral infarction were randomly divided into control group (n = 33) and control group (n = 34). Plasma fibrinogen level, clinical efficacy and incidence of adverse reactions were counted. Results the total effective rate in the observation group was 94.12% higher than that in the control group (72.73), the NIHSS score and plasma fibrinogen level in the observation group were lower than those in the control group at 1 week and 1 month after treatment, and there was no significant difference in the incidence of adverse reactions between the two groups (P 0.05). Conclusion Urethrin combined with defibrase is effective in the treatment of acute cerebral infarction. It can effectively improve the plasma fibrinogen level and the degree of nerve function defect in patients with acute cerebral infarction.
【作者單位】： 鄭州大學(xué)第五附屬醫(yī)院神經(jīng)內(nèi)科;
【基金】：國家自然科學(xué)基金資助項目(面上項目)(編號:81571137)
【分類號】：R743.33

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