發(fā)布時間：2018-04-27 09:48

  本文選題：腦梗死 + 頸動脈粥樣硬化斑塊��； 參考：《蘭州大學(xué)》2017年碩士論文

【摘要】：研究目的:研究Hcy、UA水平與腦梗死合并頸動脈粥樣硬化斑塊的相關(guān)性;研究Hcy、UA水平與腦梗死合并頸動脈粥樣硬化斑塊的斑塊性質(zhì)的關(guān)系。研究方法:隨機(jī)選取并回顧性分析2015年1月至2016年2月在蘭州大學(xué)第一醫(yī)院神經(jīng)內(nèi)科住院的腦梗死患者458例。其中腦梗死合并頸動脈粥樣硬化斑塊組(斑塊組)234例,腦梗死無頸動脈粥樣硬化斑塊組(無斑塊組)224例。所有患者行頸動脈彩超檢查明確有無斑塊及斑塊性質(zhì),行頭顱CT或MRI檢查明確腦梗死部位,并測定Hcy、UA、血脂、血糖等含量。研究結(jié)果:腦梗死合并頸動脈粥樣硬化斑塊組Hcy、UA水平高于腦梗死無頸動脈粥樣硬化斑塊組,差異有統(tǒng)計學(xué)意義(P0.01);腦梗死合并頸動脈粥樣硬化斑塊組患者中,不穩(wěn)定斑塊組Hcy、UA水平高于穩(wěn)定斑塊組,差異有統(tǒng)計學(xué)意義(P0.05)。研究結(jié)論:Hcy、UA水平可反映腦梗死合并頸動脈粥樣硬化斑塊組頸動脈斑塊的性質(zhì),不穩(wěn)定斑塊組Hcy、UA水平較穩(wěn)定斑塊組高。Hcy、UA水平增高發(fā)生不穩(wěn)斑塊的風(fēng)險越高,發(fā)生腦梗死的風(fēng)險越大。早期篩查、控制Hcy、UA水平,定期監(jiān)測頸動脈粥樣硬化斑塊并給予藥物干預(yù),對預(yù)防腦梗死發(fā)生具有臨床指導(dǎo)意義。
[Abstract]:Objective: to study the relationship between the level of Hcysillurea and carotid atherosclerotic plaque in cerebral infarction and the relationship between the level of cystatin UA and the character of plaque in cerebral infarction complicated with carotid atherosclerotic plaque. Methods: a total of 458 patients with cerebral infarction were randomly selected and analyzed retrospectively from January 2015 to February 2016 in Department of Neurology, first Hospital of Lanzhou University. There were 234 cases of cerebral infarction complicated with carotid atherosclerotic plaque group (plaque group) and 224 cases of cerebral infarction without carotid atherosclerotic plaque group (no plaque group). All the patients were examined by carotid artery color Doppler ultrasound to determine the plaques and the nature of plaques, and the location of cerebral infarction was determined by CT or MRI, and the contents of HCI UAA, blood lipids and blood glucose were measured. The results showed that the level of Hcyn UA in cerebral infarction with carotid atherosclerotic plaque group was higher than that in cerebral infarction without carotid atherosclerotic plaque group, the difference was statistically significant (P 0.01), and in the cerebral infarction with carotid atherosclerotic plaque group, the patients with cerebral infarction and carotid atherosclerotic plaque group, The level of Hcyn UA in unstable plaque group was higher than that in stable plaque group, and the difference was statistically significant (P 0.05). Conclusion the results suggest that the level of HCI UA can reflect the nature of carotid plaques in patients with cerebral infarction and carotid atherosclerotic plaques. The higher the level of Hcyn UA in unstable plaques is, the higher the risk of developing unstable plaques is. The greater the risk of cerebral infarction. Early screening, controlling the level of cystatin UA, monitoring carotid atherosclerotic plaque regularly and giving drug intervention are of clinical significance in preventing cerebral infarction.
【學(xué)位授予單位】：蘭州大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R743.3

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本文編號：1810235