本文選題：松果體區(qū)　切入點(diǎn)：腫瘤　出處：《山東大學(xué)》2014年碩士論文

【摘要】：目的 初步探討經(jīng)Poppen入路手術(shù)切除松果體區(qū)腫瘤與其他術(shù)式相比手術(shù)效果的差異。 方法 回顧性分析2010年8月至2013年10月期間在山東大學(xué)齊魯醫(yī)院初次診斷并治療的62例松果體區(qū)腫瘤患者的臨床資料,將病例分為手術(shù)組和非手術(shù)組,手術(shù)組根據(jù)手術(shù)方式不同可分為側(cè)腦室腹腔分流術(shù)、陶氏分流術(shù)、神經(jīng)內(nèi)鏡輔助下第三腦室造瘺術(shù)+腫瘤活檢術(shù),幕下小腦上入路松果體區(qū)腫瘤切除術(shù)、經(jīng)枕經(jīng)小腦幕入路松果體區(qū)腫瘤切除術(shù)、經(jīng)胼胝體后部入路松果體區(qū)腫瘤切除術(shù)等,根據(jù)術(shù)中所見(jiàn)及術(shù)后影像學(xué)檢查(頭顱CT或MRI),使用統(tǒng)計(jì)學(xué)方法檢驗(yàn)經(jīng)Poppen入路切除松果體腫瘤與其他手術(shù)方式的差異性。 以“松果體區(qū)腫瘤”、“入路”、‘"Poppen"、"顯微解剖”等作為關(guān)鍵字在Pubmed、中國(guó)知網(wǎng)等網(wǎng)站收集一系列有關(guān)于松果體區(qū)腫瘤手術(shù)治療的相關(guān)文獻(xiàn),廣泛搜索已發(fā)表的包含手術(shù)切除程度、對(duì)周圍結(jié)構(gòu)損傷等結(jié)果的中文及英文文獻(xiàn),統(tǒng)計(jì)分析所收集的數(shù)據(jù)以了解各種手術(shù)方式的差異性。 結(jié)果 經(jīng)Poppen入路手術(shù)切除松果體區(qū)腫瘤與其他手術(shù)方式相比在全切率統(tǒng)計(jì)學(xué)比較P0.05,有統(tǒng)計(jì)學(xué)意義,初步認(rèn)為經(jīng)Poppen入路全切除松果體區(qū)腫瘤的全切率優(yōu)于其他手術(shù)方式；經(jīng)Poppen入路通過(guò)腦生理間隙進(jìn)入,不損傷腦組織,手術(shù)創(chuàng)傷��；經(jīng)Poppen入路術(shù)后并發(fā)癥少,治療效果好。 結(jié)論 經(jīng)Poppen入路是治療松果體區(qū)腫瘤較安全且有效的最佳入路之一,經(jīng)腦生理間隙進(jìn)入,手術(shù)暴露效果好,創(chuàng)傷小,并發(fā)癥少,治療效果好。
[Abstract]:PurposeObjective: to explore the difference of surgical effect between Poppen approach and other surgical methods for pineal region tumor resection.MethodThe clinical data of 62 patients with pineal region tumor diagnosed and treated in Qilu Hospital of Shandong University from August 2010 to October 2013 were retrospectively analyzed. The patients were divided into operative group and non-operative group.According to the different operation methods, the operation group could be divided into three groups: lateral ventriculoperitoneal shunt, Dow shunt, neuroendoscope-assisted third ventriculostomy tumor biopsy, supratentorial superior cerebellar approach for pineal region tumor resection.Resection of tumors in pineal region via occipital approach via tentorium cerebellum, resection of tumors in pineal region via posterior approach of corpus callosum, etc.According to the intraoperative and postoperative imaging examination (CT or MRI), the difference of pineal tumor resection via Poppen approach and other surgical methods was examined by statistical method.Using "pineal region tumor", "approach", "Poppen" and "microanatomy" as keywords, we collected a series of related literatures on surgical treatment of pineal region tumor on Pubmed. China.com.In order to find out the difference of surgical methods, the published Chinese and English literatures including the degree of surgical resection and the results of peripheral structure damage were searched extensively. The collected data were statistically analyzed.ResultCompared with other surgical methods, the total removal rate of pineal region tumors by Poppen approach was significantly higher than that of other surgical methods (P 0.05). It was considered that the total removal rate of pineal region tumors via Poppen approach was better than that of other surgical methods.Poppen approach through the brain physiological space, no damage to brain tissue, the operation injury is small, the Poppen approach has few complications and good therapeutic effect.ConclusionPoppen approach is one of the most safe and effective approaches to the treatment of pineal region tumors. It has a good effect of surgical exposure, less trauma, less complications and better therapeutic effect through the brain physiological space.
【學(xué)位授予單位】：山東大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R739.41

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