本文選題：多導(dǎo)定量分析　切入點：振幅整合腦電圖　出處：《中山大學(xué)學(xué)報(醫(yī)學(xué)科學(xué)版)》2017年06期

【摘要】：【目的】探討腦損傷兒童振幅整合腦電圖(a EEG)改變以及與神經(jīng)系統(tǒng)早期預(yù)后的關(guān)系�！痉椒ā坎捎�16導(dǎo)聯(lián)的a EEG監(jiān)測模式對100例腦損傷患兒(腦損傷組)及100例正常兒童(對照組)進行監(jiān)測。對兩組兒童不同年齡段額、中央、頂、顳區(qū)的波譜進行比較,比較腦損傷組兒童急性期及1周后a EEG特點,分析腦損傷兒童的a EEG特點。同時隨訪記錄3個月后腦損傷組兒童腦功能等級評分(PCPC),并評價腦損傷兒童a EEG的變化與PCPC評分的相關(guān)性�！窘Y(jié)果】2-12月正常嬰兒與異常嬰兒下邊界電壓相比額區(qū)、顳區(qū)明顯增高(P0.05);帶寬的比較,額區(qū)、中央?yún)^(qū)、顳區(qū)腦損傷嬰兒較正常嬰兒明顯降低(P0.05)。13-35月的腦損傷兒童與正常對照組a EEG比較表明:所有導(dǎo)聯(lián)的上邊界及下邊界電壓均較正常組明顯增高(P0.05)。36-71月腦損傷兒童與正常兒童下邊界電壓相比額區(qū)、中央?yún)^(qū)、頂區(qū)、顳區(qū)明顯增高(P0.05);上邊界的比較中僅額區(qū)、頂區(qū)差異具有統(tǒng)計學(xué)意義(P0.05)。72-155月腦損傷兒童與正常兒童下邊界電壓相比額區(qū)、中央?yún)^(qū)、頂區(qū)、顳區(qū)明顯增高(P0.05);上邊界的比較中僅額區(qū)、中央?yún)^(qū)、頂區(qū)差異具有統(tǒng)計學(xué)意義(P0.05);帶寬比較額區(qū)、頂區(qū)兩組間比較差異有統(tǒng)計學(xué)意義(P0.05)。156-216月腦損傷兒童與正常兒童下邊界電壓相比額區(qū)、中央?yún)^(qū)、頂區(qū)、顳區(qū)明顯增高(P0.05);上邊界的比較中額區(qū)、中央?yún)^(qū)、頂區(qū)、顳區(qū)明顯增高(P0.05);帶寬比較僅額區(qū)兩組間比較差異有統(tǒng)計學(xué)意義(P0.05)。腦損傷患兒3個月后的PCPC評分與患兒a EEG進行相關(guān)分析表明頂區(qū)上邊界、下邊界存在相關(guān)性,相關(guān)系數(shù)分別為0.222,0.219�！窘Y(jié)論】腦損傷兒童的各導(dǎo)聯(lián)下邊界電壓發(fā)生改變,腦損傷患兒早期頂區(qū)a EEG定量值可用于預(yù)測患兒的近期預(yù)后。
[Abstract]:[objective] to investigate the changes of amplitude-integrated electroencephalogram (EEG) and its relationship with early prognosis of nervous system in children with brain injury. [methods] A EEG monitoring model with 16 leads was used in 100 children with brain injury (brain injury group) and 100 patients with positive brain injury. Normal children (control group) were monitored. The spectra of central, parietal and temporal regions were compared to compare the characteristics of a EEG in acute stage and 1 week after brain injury group. To analyze the characteristics of a EEG in children with brain injury, and to record the scores of brain function grade in children with brain injury after 3 months of follow-up, and to evaluate the correlation between the changes of a EEG and PCPC score in children with brain injury. [results] the normal infants and abnormal infants in February to December were evaluated. Infantile lower boundary voltage compared to frontal region, The temporal region was significantly increased (P 0.05), the bandwidth was compared, the frontal region, the central region, the central region, the frontal region, the central region, Compared with the normal control group, the EEG of children with brain injury in temporal region was significantly lower than that of normal infants. The results showed that the voltage of upper boundary and lower boundary of all leads were significantly higher than that of normal group. P0.05. 36-71 months of brain injury in children with brain injury and normal were significantly higher than those in normal group. Children's lower boundary voltage compared to the frontal region, The central, parietal and temporal regions were significantly higher than that of normal children, and the frontal, central and parietal areas were significantly higher than those in normal children, while the frontal, central and parietal areas were significantly higher than those in normal children. The difference in parietal area was significant in the frontal area, central region and parietal area in children with brain injury during the period of 72-155 months compared with those in normal children. There were significant differences in the temporal region, the upper border, the frontal region, the central region and the parietal region, and the difference in the bandwidth between the frontal region, the central region and the parietal region, and the comparison of the bandwidth between the frontal region and the parietal region. The difference between the two groups was statistically significant (P 0.05). 156-216 months after brain injury compared with normal children, the lower boundary voltage in frontal, central, parietal and temporal regions were significantly higher than those in normal children, and the middle frontal, central and parietal regions in the comparison of upper border, middle frontal, central and parietal regions. There was significant difference in the bandwidth between the two groups only in the frontal area. The correlation analysis between the PCPC scores of the children with brain injury and the a EEG showed that there was a correlation between the upper and lower boundaries of the parietal region. The correlation coefficients were 0.222n0.219.Conclusion the voltage of the lower lead of children with brain injury changes, and the quantitative value of a EEG in the early parietal region can be used to predict the short-term prognosis of the children with brain injury.
【作者單位】： 中山大學(xué)附屬第一醫(yī)院婦產(chǎn)科;四川大學(xué)華西第二醫(yī)院兒科;
【分類號】：R726.5;R741.044

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