顱內(nèi)腦膜瘤單中心845例臨床病理分析
發(fā)布時(shí)間:2018-03-26 15:07
本文選題:腦膜瘤 切入點(diǎn):生存分析 出處:《廣東醫(yī)學(xué)》2017年24期
【摘要】:目的分析15年間單中心顱內(nèi)腦膜瘤患者臨床及病理特征和治療效果。方法回顧性分析845例手術(shù)治療的腦膜瘤患者的臨床病理及預(yù)后資料,應(yīng)用Kaplan-Meier法、log-rank檢驗(yàn)和Cox回歸模型對(duì)性別、年齡、WHO病理級(jí)別、術(shù)前KPS評(píng)分等臨床病理特征進(jìn)行單因素和多因素生存分析。結(jié)果 845例腦膜瘤患者中男235例,女610例,年齡(49.96±12.17)歲,總隨訪時(shí)間1~240個(gè)月,中位隨訪時(shí)間5.00個(gè)月。57例術(shù)后復(fù)發(fā),其中WHOⅠ級(jí)腦膜瘤復(fù)發(fā)36例(4.9%,36/732),WHOⅡ級(jí)腦膜瘤復(fù)發(fā)14例(17.1%,14/82),WHOⅢ級(jí)腦膜瘤復(fù)發(fā)7例(7/31)。WHO病理分級(jí)高和男性是腦膜瘤復(fù)發(fā)高危因素。結(jié)論 WHOⅡ和Ⅲ級(jí)腦膜瘤手術(shù)后易復(fù)發(fā),對(duì)于高;颊咝枰扇》e極輔助治療并嚴(yán)密隨訪。
[Abstract]:Objective to analyze the clinical and pathological features and therapeutic efficacy of patients with monocentric meningioma during the past 15 years. Methods the clinicopathological and prognostic data of 845 patients with intracranial meningioma treated by surgery were analyzed retrospectively, and the sex was analyzed by Kaplan-Meier 's log-rank test and Cox regression model. Results among 845 patients with meningioma, 235 were male, 610 were female, the age was 49.96 鹵12.17 years old, and the total follow-up time was 1 ~ 240 months. The median follow-up time was 5.00 months. Among the 36 cases of WHO 鈪,
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