本文選題：LA　切入點(diǎn)：危險(xiǎn)因素　出處：《福建醫(yī)科大學(xué)》2014年碩士論文　論文類(lèi)型：學(xué)位論文

【摘要】：目的：探討腦白質(zhì)疏松癥(leukoaraiosis LA)相關(guān)危險(xiǎn)因素。 方法:對(duì)收治的164例LA患者（LA組）及104例非LA患者（非LA組）的性別、年齡、高血壓、糖尿病、吸煙、飲酒、血脂異常、血漿纖維蛋白原、空腹血糖、D二聚體、尿酸、血清白蛋白、同型半胱氨酸等指標(biāo)進(jìn)行調(diào)查評(píng)估，對(duì)LA的相關(guān)危險(xiǎn)因素進(jìn)行分析。 結(jié)果：LA組的患者患有糖尿病、高血壓、吸煙、飲酒的比例明顯比非LA組高（P0.05）；與非LA組相比，LA組尿酸（356.49±121.85vs289.96±102.98，P=0.000）、年齡（65.43±9.56vs52.77±7.05,p=0.000）、血漿纖維素原（3.28±0.84vs2.86±0.67，，p=0.000）、同型半胱氨酸（15.57±6.22vs12.74±4.93、p=0.000）、血清白蛋白(49.95±5.06vs43.52±3.61、p=0.006)、空腹血糖（5.79±2.87vs5.14±0.64、p=0.026）、高密度脂蛋白(1.19±0.41vs1.34±0.48、p=0.006）、低密度脂蛋白（2.95±1.06vs2.70±0.96、p=0.049）兩組具有明顯的統(tǒng)計(jì)學(xué)差異（P0.05）。經(jīng)logistic多因素回歸分析，高血壓、年齡、Hcy、尿酸、血清白蛋白血與LA的發(fā)生獨(dú)立相關(guān)。 結(jié)論：說(shuō)明高血壓、年齡、Hcy、尿酸、血清白蛋白低是LA的獨(dú)立危險(xiǎn)因素。
[Abstract]:Objective: to investigate the risk factors of leukoaraiosis in leukoaraiosis. Methods: sex, age, hypertension, diabetes, smoking, alcohol consumption, dyslipidemia, plasma fibrinogen, fasting blood glucose D-dimer, uric acid were studied in 164 LA patients and 104 non-LA patients (non-LA group). Serum albumin and homocysteine were investigated and evaluated to analyze the risk factors of LA. Results the patients in the% LA group had diabetes, high blood pressure, smoking, Compared with the non-LA group, the ratio of drinking alcohol was significantly higher than that of the non-LA group (356.49 鹵102.98 121.85vs289.96 鹵102.98), the age was 65.43 鹵7.05 9.56vs52.77 鹵7.05, the plasma fibrinogen was 3.28 鹵0.67p0.000, the homocysteine was 15.57 鹵4.93, the serum albumin was 49.95 鹵3.61, the fasting blood glucose was 5.79 鹵0.64p0.026, the high density lipoprotein was 1.19 鹵0.48pP, the low density lipoprotein was 2.95 鹵1.06vs2.70 鹵0.96p0.049). The statistical difference was significant (P 0.05). By logistic multivariate regression analysis, Hypertension, age, uric acid, serum albumin and LA were independently associated. Conclusion: hypertension, age, uric acid, serum albumin are independent risk factors of LA.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類(lèi)號(hào)】：R744.5

【參考文獻(xiàn)】

相關(guān)期刊論文 前6條

1 張東平;張波;胡長(zhǎng)林;;腦小血管病及其亞型與頸動(dòng)脈粥樣硬化的相關(guān)性[J];中國(guó)動(dòng)脈硬化雜志;2008年06期

2 郭洪志;腦白質(zhì)疏松癥[J];臨床神經(jīng)病學(xué)雜志;2002年01期

3 徐燕;李永杰;高旭光;;原發(fā)性高血壓患者微量白蛋白尿與無(wú)癥狀性腦血管損害的研究[J];中華老年心腦血管病雜志;2007年11期

4 高娜;趙鐵耘;李秀鈞;;糖尿病是卒中的獨(dú)立危險(xiǎn)因素[J];中國(guó)卒中雜志;2007年07期

5 齊冬;王春雪;賈茜;鄭華光;;糖代謝異常與腦白質(zhì)疏松相關(guān)性初步研究[J];中國(guó)卒中雜志;2010年04期

6 許盈盈;蔡若蔚;;慢性阻塞性睡眠呼吸暫停綜合征白質(zhì)腦病與認(rèn)知功能改變關(guān)系的研究[J];中國(guó)校醫(yī);2011年04期

本文編號(hào)：1645086