本文選題：椎動(dòng)脈發(fā)育不良　切入點(diǎn)：磁共振血管造影　出處：《新鄉(xiāng)醫(yī)學(xué)院》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的探討椎動(dòng)脈發(fā)育不良與后循環(huán)缺血的關(guān)系,研究椎動(dòng)脈發(fā)育不良的MRA初步分型及其臨床意義。方法收集2011年5月至2014年3月在南陽(yáng)中心醫(yī)院神經(jīng)內(nèi)科門診及住院的患者,選取行頭部/頸部MRA檢查,同時(shí)行顱腦磁共振平掃檢查的患者862例。根據(jù)椎動(dòng)脈發(fā)育不良診斷標(biāo)準(zhǔn),分為椎動(dòng)脈發(fā)育不良組80例(觀察組),無椎動(dòng)脈發(fā)育不良組782例(對(duì)照組),比較兩組間后循環(huán)TIA及后循環(huán)梗死的總發(fā)生率,統(tǒng)計(jì)分析椎動(dòng)脈發(fā)育不良與后循環(huán)TIA和后循環(huán)梗死的相關(guān)性。通過80例椎動(dòng)脈發(fā)育不良患者的MRA特點(diǎn)和臨床資料,對(duì)其進(jìn)行分型,分析不同分型與后循環(huán)TIA及腦梗死的相關(guān)性。結(jié)果在862例患者中,椎動(dòng)脈發(fā)育不良80例,其中右側(cè)54例,左側(cè)26例；后循環(huán)TIA 51例,發(fā)生率63.75%,后循環(huán)腦梗死23例,發(fā)生率28.75%,其中前循環(huán)缺血表現(xiàn)為6例；其余782例患者中,前循環(huán)缺血表現(xiàn)626例,后循環(huán)缺血表現(xiàn)156例,發(fā)生率19.95%,其中后循環(huán)TIA 97例,發(fā)生率12.40%；后循環(huán)梗死59例,發(fā)生率7.54%；兩組比較P=0.000,差異具有統(tǒng)計(jì)學(xué)意義。椎動(dòng)脈發(fā)育不良根據(jù)MRA表現(xiàn)分為Ⅳ型,其中Ⅰ型11例,發(fā)生后循環(huán)TIA 9例,發(fā)生率81.82%,腦梗死1例,發(fā)生率9.09%；Ⅱ型28例,發(fā)生后循環(huán)TIA 21例,發(fā)生率75.00%,腦梗死5例,發(fā)生率17.86%；Ⅲ型24例,發(fā)生后循環(huán)TIA 15例,發(fā)生率62.50%,腦梗死7例,發(fā)生率29.17%；Ⅳ型17例,發(fā)生后循環(huán)TIA 6例,發(fā)生率35.29%,腦梗死10例,發(fā)生率58.82%。結(jié)論(1).椎動(dòng)脈發(fā)育不良與后循環(huán)TIA和后循環(huán)梗死有明顯的相關(guān)性,是缺血性腦卒中的危險(xiǎn)因素；(2).根據(jù)MRA影像學(xué)表現(xiàn),可將椎動(dòng)脈發(fā)育不良分為Ⅳ型,椎動(dòng)脈發(fā)育不良分型越高,發(fā)生腦梗死的風(fēng)險(xiǎn)越大。
[Abstract]:Objective to investigate the relationship between vertebral artery dysplasia and posterior circulation ischemia, and to study the MRA classification of vertebral artery dysplasia and its clinical significance. Methods from May 2011 to March 2014, we collected the patients in the Department of Neurology, Nanyang Central Hospital. According to the diagnostic criteria of vertebral artery dysplasia, 862 patients were selected for head / neck MRA examination and brain MRI plain scan. There were 80 cases of vertebral artery dysplasia (observation group) and no vertebral artery dysplasia group (782 cases) (control group). The total incidence of posterior circulation TIA and posterior circulation infarction were compared between the two groups. The correlation between vertebral artery dysplasia and posterior circulation TIA and posterior circulation infarction was statistically analyzed. The MRA characteristics and clinical data of 80 patients with vertebral artery dysplasia were classified. Results among 862 patients, 80 cases had dysplasia of vertebral artery, including 54 cases on right side, 26 cases on left side, 51 cases on posterior circulation TIA, and 23 cases on posterior circulation cerebral infarction. The incidence rate was 28.75%, including 6 cases of anterior circulation ischemia, 626 cases of anterior circulation ischemia and 156 cases of posterior circulation ischemia, of which 97 cases were posterior circulation TIA (12.40%), 59 cases were posterior circulation infarction. Vertebral artery dysplasia was divided into four types according to MRA manifestation, 11 cases of type 鈪，

本文編號(hào)：1583006