基于TOAST和ASCO分型的輕型卒中病因?qū)W分型研究
發(fā)布時(shí)間:2018-03-04 21:27
本文選題:輕型卒中 切入點(diǎn):病因分型 出處:《四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年03期 論文類型:期刊論文
【摘要】:目的研究輕型卒中與非輕型卒中病因?qū)W分型的差異,指導(dǎo)輕型卒中早期針對病因?qū)W的干預(yù)措施。方法回顧性納入2012年7月至2014年7月于四川大學(xué)華西醫(yī)院神經(jīng)內(nèi)科住院治療的急性缺血性卒中患者,采用TOAST分型標(biāo)準(zhǔn)和ASCO分型標(biāo)準(zhǔn)對輕型卒中患者及非輕型卒中患者進(jìn)行病因分型,對比兩者在病因?qū)W分布上的差異。結(jié)果共納入輕型卒中患者406例,非輕型卒中患者651例。兩組TOAST分型構(gòu)成比不同(P0.001),其中輕型卒中組小動(dòng)脈閉塞(SAO)比率最高,為40.4%(164例),非輕型卒中組原因未明型(SUE)比率最高,為30.9%(201例);輕型卒中組A1+2及C1+2占比均低于非輕型卒中組(22.8%vs.35.4%,P0.001;19.3%vs.32.1%,P0.001),S1+2占比高于非輕型卒中組(49.8%vs.27.3%,P0.001)。結(jié)論輕型卒中與非輕型卒中相比,病因?qū)W分型存在差異。輕型卒中小動(dòng)脈閉塞病因占比更高,而非輕型卒中心源性栓塞及大動(dòng)脈粥樣硬化性病因占比更高。
[Abstract]:Objective to study the difference of etiological classification between mild stroke and non-mild stroke. Methods Acute ischemic stroke patients who were hospitalized in Department of Neurology, West China Hospital, Sichuan University from July 2012 to July 2014 were included retrospectively. TOAST classification criteria and ASCO classification criteria were used to classify the etiology of mild stroke patients and non-mild stroke patients, and the differences of etiological distribution between the two groups were compared. Results A total of 406 patients with mild stroke were included. There were 651 patients with non-mild stroke. The ratio of TOAST classification was different (P 0.001). The ratio of small artery occlusion (SAO) in mild stroke group was the highest (40.4%), and the ratio of unknown type sue in non-mild stroke group was the highest. The proportion of A1 2 and C 12 in mild stroke group was lower than that in non-mild stroke group. Conclusion compared with non-mild stroke group, the ratio of light stroke group to non-mild stroke group is higher than that of non-mild stroke group, and the ratio of light stroke group to non-mild stroke group is higher than that of non-mild stroke group, and the ratio of light stroke group to non-mild stroke group is higher than that of non-mild stroke group, and the ratio of light stroke group to non-mild stroke group is higher than that of non-mild stroke group, and the ratio of mild stroke group to non-mild stroke group is higher than that of non-mild stroke group. The causes of arteriole occlusion in mild stroke were higher than those in non-mild stroke, and the causes of cardiogenic embolism and atherosclerosis were higher than those of non-mild stroke.
【作者單位】: 四川大學(xué)華西醫(yī)院神經(jīng)內(nèi)科;
【基金】:國家自然科學(xué)基金(No.81472162) 四川省科技廳科技支撐計(jì)劃項(xiàng)目(No.2014SZ0005-3)資助
【分類號(hào)】:R743.3
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