低氧死腔通氣與屏氣試驗(yàn)對(duì)腦血管反應(yīng)性測(cè)試的對(duì)比觀察
本文關(guān)鍵詞: 腦血管反應(yīng)性 低氧死腔通氣 屏氣試驗(yàn) TCD 出處:《臨床神經(jīng)病學(xué)雜志》2017年02期 論文類型:期刊論文
【摘要】:目的通過(guò)低氧死腔通氣與屏氣試驗(yàn)的對(duì)比,探討低氧死腔通氣在血管運(yùn)動(dòng)反應(yīng)性(VMR)測(cè)試中的應(yīng)用前景。方法選擇門診或住院進(jìn)行TCD檢測(cè)的患者,先后進(jìn)行屏氣試驗(yàn)及低氧死腔通氣,并計(jì)算其VMR進(jìn)行對(duì)比分析。記錄患者的配合程度、耐受情況及不良反應(yīng)。結(jié)果入組35例患者,屏氣試驗(yàn)有7例(20%)患者因配合不佳退出研究,而低氧死腔通氣僅有2例(5.71%)因配合不佳退出,最終26例患者納入研究。屏氣試驗(yàn)除屏氣后代償性呼吸增快外,基本沒(méi)有不良反應(yīng);低氧死腔通氣不良反應(yīng)主要表現(xiàn)在通氣末期呼吸頻率加快加深,心率增快,脈氧輕度下降,但停止通氣后很快恢復(fù)。納入研究的26例患者在屏氣試驗(yàn)前及低氧死腔通氣前的平均血流速度差異無(wú)統(tǒng)計(jì)學(xué)意義。在屏氣試驗(yàn)后及低氧死腔通氣后平均血流速度均明顯升高,且二者相關(guān)性良好(P0.001),低氧死腔通氣的VMR值明顯高于屏氣試驗(yàn)(P0.001)。屏氣試驗(yàn)平均血流速度曲線表現(xiàn)為輕度下降后迅速升高的單向曲線,而低氧死腔通氣則表現(xiàn)為短時(shí)下降后較緩上升的曲線,有一平臺(tái)期。結(jié)論低氧死腔通氣可以有效改善患者不能配合的影響,避免缺氧造成不耐受,所測(cè)定的VMR值較屏氣試驗(yàn)更加精確,并且能反應(yīng)血管的最大反應(yīng)能力,具有更高的臨床應(yīng)用價(jià)值。
[Abstract]:Objective to explore the application prospect of hypoxic dead chamber ventilation in VMRs by comparing hypoxic dead chamber ventilation with breath-holding test. Breath holding test and hypoxic dead chamber ventilation were carried out successively, and their VMR were calculated for comparative analysis. The degree of cooperation, tolerance and adverse reactions of the patients were recorded. Results 35 patients were enrolled in the study, 7 patients in the breath-holding test, and 7 patients withdrew from the study because of poor cooperation. However, only 2 cases of hypoxic dead chamber ventilation withdrew due to poor coordination, and 26 patients were included in the study. Except for the compensatory respiratory acceleration after breath-holding, there was basically no adverse reaction in the breath-holding test. The main adverse effects of hypoxic dead chamber ventilation were the acceleration and deepening of respiratory rate, the increase of heart rate and the slight decrease of pulse oxygen at the end of ventilation. However, there was no significant difference in the mean blood flow velocity before the breath holding test and before the hypoxic dead chamber ventilation in the 26 patients who were enrolled in the study. The mean blood flow velocity increased significantly after the breath-holding test and after the hypoxic dead chamber ventilation. The VMR value of hypoxic dead chamber ventilation was significantly higher than that of breath-holding test (P0.001). The mean blood flow velocity curve of breath-holding test was a one-way curve that increased rapidly after a slight decrease. However, hypoxic dead chamber ventilation showed a slowly rising curve after a short period of decline. Conclusion hypoxic dead chamber ventilation can effectively improve the effect that patients can not cooperate and avoid intolerance caused by hypoxia. The measured VMR value is more accurate than the breath-holding test, and can reflect the maximum response ability of the blood vessel, so it has higher clinical application value.
【作者單位】: 南京醫(yī)科大學(xué)附屬淮安第一醫(yī)院神經(jīng)內(nèi)科;
【分類號(hào)】:R743
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