妊娠和產(chǎn)褥期上矢狀竇血栓形成的發(fā)病時(shí)間與臨床特征的分析研究
發(fā)布時(shí)間:2018-02-16 22:32
本文關(guān)鍵詞: 妊娠 產(chǎn)褥期 腦卒中 上矢狀竇 栓塞 出處:《中南大學(xué)》2014年碩士論文 論文類型:學(xué)位論文
【摘要】:目的:回顧性分析2002-2013年國內(nèi)243例妊娠和產(chǎn)褥期上矢狀竇血栓形成患者的發(fā)病時(shí)間、臨床特征和影像學(xué)檢查的資料,為早期診斷妊娠和產(chǎn)褥期上矢狀竇血栓形成提供依據(jù)。 資料與方法:利用相關(guān)期刊論文,檢索2002-2013年國內(nèi)報(bào)道及我院收集的共243例妊娠和產(chǎn)褥期上矢狀竇血栓形成患者的臨床資料,按產(chǎn)前、產(chǎn)時(shí)及產(chǎn)后三個(gè)發(fā)病階段,分析研究妊娠和產(chǎn)褥期上矢狀竇血栓形成患者的臨床特征、診斷、影像學(xué)的改變與預(yù)后。 結(jié)果:243例妊娠和產(chǎn)褥期上矢狀竇血栓形成患者中,產(chǎn)前及產(chǎn)時(shí)發(fā)病患者均以急性發(fā)病,誤診率及死亡率分別高達(dá)70%、60%,分別占總病例數(shù)的2.9%和1.2%;且顱壓增高的發(fā)生率均為100%,抽搐的發(fā)生率為85.7%和100%,意識(shí)改變的發(fā)生率為71.4%和66.7%,肌力下降或肢體癱瘓的發(fā)生率為57.1%和33.3%。產(chǎn)后發(fā)病者以亞急性或急性起病,誤診率及死亡率分別為2.6%和7.3%,病例數(shù)占95.9%。上述4種臨床特征發(fā)生率的比例依次為87.6%、53.6%、43.8%和45.9%。CT檢查和MRI/MRV檢查的陽性率分別為33.3%和100%。 結(jié)論:產(chǎn)褥早期是妊娠和產(chǎn)褥期上矢狀竇血栓形成患者高發(fā)時(shí)期。產(chǎn)前及產(chǎn)時(shí)發(fā)病的患者病情發(fā)展快,誤診率及死亡率高。對(duì)產(chǎn)前疑似的患者應(yīng)盡早進(jìn)行MRI/MRV確診并給以及時(shí)有效的治療。
[Abstract]:Objective: to analyze retrospectively 243 cases of superior sagittal sinus thrombosis during pregnancy and puerperium in China from 2002 to 2013, and to provide evidence for early diagnosis of superior sagittal sinus thrombosis in pregnancy and puerperium. Materials and methods: a total of 243 cases of upper sagittal sinus thrombosis in pregnancy and puerperium were collected from 2002 to 2013 by using the full text database of Chinese periodicals. To study the clinical features, diagnosis, imaging changes and prognosis of patients with superior sagittal sinus thrombosis during pregnancy and puerperium. Results among 243 cases of upper sagittal sinus thrombosis during pregnancy and puerperium, acute onset was found in prenatal and parturient patients. The misdiagnosis rate and mortality rate were as high as 70% and 60%, accounting for 2.9% and 1.2% of the total cases, respectively, and the incidence of intracranial hypertension was 100, the incidence of convulsions was 85.7% and 100, the incidence of consciousness change was 71.4% and 66.7, and the incidence of myoplegia or limb paralysis was 71.4% and 66.7 respectively. 57.1% and 33. 3. The postpartum onset was subacute or acute. The misdiagnosis rate and mortality rate were 2.6% and 7.3, respectively. The incidence rates of the four clinical characteristics were 87.6% and 43.8%, respectively, and the positive rates of CT and MRI/MRV were 33.3% and 100, respectively. Conclusion: the early puerperal period is the period of high incidence of superior sagittal sinus thrombosis in pregnancy and puerperium. The misdiagnosis rate and mortality rate are high. MRI/MRV diagnosis and prompt and effective treatment should be carried out as soon as possible for suspected prenatal patients.
【學(xué)位授予單位】:中南大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R743.3
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