檸檬精油對牙周病主要致病菌粘附作用影響的體外研究
發(fā)布時間:2018-03-26 13:46
本文選題:檸檬精油 切入點:牙周病 出處:《口腔醫(yī)學研究》2015年07期
【摘要】:目的:研究檸檬精油(LEO)對牙周病主要致病菌黏附作用的影響,探討其用于預(yù)防和治療牙周病的可行性。方法:光滑聚苯乙烯表面黏附的影響:將菌液與實驗分組中各組藥液混合培養(yǎng)于96孔板48h,檢測各孔內(nèi)細菌附著情況;蛋白包被聚苯乙烯表面黏附的影響:將菌液與實驗分組中各組藥液混合培養(yǎng)于形成蛋白包被表面的96孔板48h,檢測各孔內(nèi)細菌附著情況。結(jié)果:光滑聚苯乙烯表面黏附的影響:Aa、Pi中LEO組與對照組比較差異無統(tǒng)計學意義,Pg、Fn中LEO組與對照組比較差異有統(tǒng)計學意義(P0.05);蛋白包被聚苯乙烯表面黏附的影響:Aa、Pg、Pi、Fn中LEO組與對照組比較差異有統(tǒng)計學意義(P0.05),LEO能抑制Aa、Pg、Pi、Fn在蛋白包被表面的黏附,對Pg、Fn在光滑聚苯乙烯表面的黏附也有抑制作用。結(jié)論:LEO能抑制病原菌對牙面的黏附,阻斷牙菌斑的形成,具有預(yù)防牙周病的作用。
[Abstract]:Objective: to study the effect of Lemon essential Oil (Lemon) on adhesion of periodontal disease pathogens. Methods: the effect of smooth polystyrene surface adhesion was studied. Effect of protein coated polystyrene surface adhesion: bacteria solution was mixed with each group of drug solution in experimental group and cultured on 96 well plate of protein coated surface for 48 h. Results: smooth polystyrene surface was smooth. There was no significant difference between the LEO group and the control group. There was a significant difference between the LEO group and the control group, and there was a significant difference between the LEO group and the control group in the surface adhesion of protein coated polystyrene. The statistical significance was that P0. 05 triptolide could inhibit the adhesion of AaGG to the surface of the protein coated with P0. 05, P0. 05, and P0. 05, and P0. 05. Conclusion:% Leo can inhibit the adhesion of pathogenic bacteria to tooth surface, block the formation of dental plaque, and prevent periodontal disease.
【作者單位】: 天津市口腔醫(yī)院兒童牙病科;天津醫(yī)科大學口腔醫(yī)學院;
【基金】:天津市衛(wèi)生局科技基金(編號:2011ky16)
【分類號】:R781.4
【參考文獻】
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