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抑郁性障礙患者的癥狀特點(diǎn)及其與述情障礙特征的關(guān)系

發(fā)布時間:2019-05-22 23:13
【摘要】:目的:(1)了解不同性別、來源地、年齡、文化程度抑郁性障礙患者的抑郁癥狀表現(xiàn)特點(diǎn)。(2)探討抑郁性障礙患者的癥狀表現(xiàn)與述情障礙特征的關(guān)系。 方法:抑郁組307例,分別來自長沙和懷化地區(qū)的四家醫(yī)院,所有入選病例均具有符合DSM-IV診斷標(biāo)準(zhǔn)中抑郁發(fā)作的核心癥狀。正常對照組351例來自門診就診患者家屬(或陪護(hù)人員)。對抑郁組采用結(jié)構(gòu)式訪談了解其臨床癥狀。對所有研究對象采用流調(diào)中心用抑郁量表(CES-D)評估其抑郁癥狀及抑郁水平,使用多倫多述情障礙量表(TAS-20)中文版測查其述情障礙特征。 結(jié)果:(1)抑郁組與正常對照組在CES-D的抑郁情緒、軀體癥狀、積極情緒及人際關(guān)系四個因子的得分和量表總分上存在顯著差異,抑郁組的得分均顯著高于正常對照組(P0.001)。(2)男性抑郁性障礙患者的抑郁情緒因子分顯著低于女性(P0.01);不同文化程度的抑郁性障礙患者的抑郁情緒因子分、軀體癥狀因子分以及CES-D總分存在顯著差異,文化程度在小學(xué)及以下的抑郁性障礙患者的抑郁情緒因子分、軀體癥狀因子分、CES-D總分明顯高于其他文化程度的抑郁性障礙患者(P0.05);不同年齡、不同來源地的抑郁性障礙患者的抑郁癥狀無顯著差異;(3)抑郁組與正常對照組在TAS-20的情感辨別困難、情感描述困難及外向性思維三個因子的得分和量表總分上存在顯著差異,抑郁組的得分均顯著高于正常對照組(P0.01)。(4)抑郁性障礙患者的CES-D總分與情感辨別困難因子分、情感描述困難因子分、TAS-20總分均顯著相關(guān)(P0.05);抑郁情緒因子分與情感辨別困難因子分、情感描述困難因子分、外向性思維因子分及TAS-20總分均顯著相關(guān)(相關(guān)系數(shù)為0.122~0.169,P0.05或P0.01);軀體癥狀因子分與情感辨別困難因子分、情感描述困難因子分、外向性思維因子分及TAS-20總分均顯著相關(guān)(P0.05);積極情緒因子分與外向性思維因子分顯著相關(guān)(P0.05);人際困難因子分與TAS-20總分顯著相關(guān)(P0.05)。高述情障礙抑郁性障礙患者組的CES-D總分、抑郁情緒及軀體癥狀因子分均顯著高于低述情障礙抑郁性障礙患者組(P0.05)。 結(jié)論: (1)抑郁性障礙患者的抑郁嚴(yán)重程度以及抑郁癥狀表現(xiàn)存在性別和文化程度的差異; (2)抑郁性障礙患者相對健康人群表現(xiàn)出更明顯的述情障礙; (3)抑郁性障礙患者的癥狀表現(xiàn)與其述情障礙有關(guān),高述情障礙的抑郁性障礙患者表現(xiàn)出更嚴(yán)重的抑郁癥狀,更容易表現(xiàn)出軀體化癥狀。表8張,參考文獻(xiàn)86
[Abstract]:Objective: (1) to understand the characteristics of depressive symptoms in patients with depressive disorder of different sex, origin, age and educational level. (2) to explore the relationship between the symptoms of depressive disorders and the characteristics of alexithymia. Methods: 307 patients in depression group were from four hospitals in Changsha and Huaihua respectively. All the selected patients had the core symptoms of depression according to the diagnostic criteria of DSM-IV. In the normal control group, 351 cases came from the family members (or accompanying personnel) of the outpatients. The clinical symptoms of depression group were investigated by structural interview. The depressive symptoms and depression level were evaluated by flow center depression scale (CES-D), and the characteristics of alexithymia were measured by Toronto alexithymia scale (TAS-20) in Chinese. Results: (1) there were significant differences in the scores of depression, physical symptoms, positive emotion and interpersonal relationship between the depression group and the normal control group, as well as the total score of the scale. The scores of depression in depression group were significantly higher than those in normal control group (P0. 001). (2). The scores of depression factor in male patients with depressive disorder were significantly lower than those in women (P 0.01). There were significant differences in depression factor score, somatic symptom factor score and CES-D total score among patients with depressive disorder with different educational levels. the scores of depression factor in patients with depressive disorder with educational level below primary school were significantly different. The score of somatic symptom factor and the total score of CES-D were significantly higher than those of patients with depressive disorder with other educational levels (P 0.05). There was no significant difference in depressive symptoms among patients with depressive disorder of different ages and different places of origin. (3) there were significant differences in the scores of emotional discrimination difficulty, emotional description difficulty and extroverted thinking between the depression group and the normal control group, and the total score of the scale. The scores of depression group were significantly higher than those of normal control group (P 0.01). (4). The total score of CES-D was significantly correlated with the score of emotion discrimination difficulty factor, emotion description difficulty factor and TAS-20 score of patients with depression disorder (P 0.05). Depression emotion factor score was significantly correlated with emotion discrimination difficulty factor score, emotion description difficulty factor score, extroverted thinking factor score and TAS-20 total score (correlation coefficient was 0.122 鹵0.169, P 0.05 or P 0.01), and there was a significant correlation between depression emotion factor score and emotion discrimination difficulty factor score, emotion description difficulty factor score, extroversion thinking factor score and TAS-20 total score. Somatic symptom factor score was significantly correlated with emotion discrimination difficulty factor score, emotion description difficulty factor score, extroversion thinking factor score and TAS-20 total score (P 0.05). The positive emotion factor score was significantly correlated with the extroversion thinking factor score (P 0.05), and the interpersonal difficulty factor score was significantly correlated with the total score of TAS-20 (P 0.05). The total score of CES-D, depressive mood and somatic symptom factors in patients with depression disorder were significantly higher than those in patients with depression disorder (P 0.05), and the scores of total score, depression emotion and somatic symptoms in patients with depression disorder were significantly higher than those in patients with depression disorder (P 0.05). Conclusion: (1) there are gender and educational differences in the severity of depression and depressive symptoms in patients with depressive disorder, (2) patients with depressive disorder show more obvious alexithymia than healthy people, and (2) there are more obvious alexithymia in patients with depressive disorder than in healthy people. (3) the symptoms of patients with depressive disorder were related to alexithymia. Patients with depressive disorder with high alexithymia showed more serious depressive symptoms and were more likely to show somatization symptoms. Table 8, references 86
【學(xué)位授予單位】:中南大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2013
【分類號】:R749.4

【參考文獻(xiàn)】

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