有沖動攻擊行為的雙相情感障礙患者認(rèn)知功能研究
發(fā)布時(shí)間:2019-05-21 20:43
【摘要】:目的:探討伴有沖動攻擊行為的雙相情感障礙患者其認(rèn)知功能損害的特征,以及雙相情感障礙患者的沖動攻擊行為是否會進(jìn)一步加重認(rèn)知功能的損害,為認(rèn)知功能損害的預(yù)防和干預(yù)提供科學(xué)的理論依據(jù)。方法:本研究采用橫斷面研究的方法,將于2015年10月至2016年08月,在新疆維吾爾自治區(qū)人民醫(yī)院臨床心理科住院,并愿意接受調(diào)查的72例雙相情感障礙患者進(jìn)行研究。量表包括,自編一般情況調(diào)查表、輕躁狂癥狀量表(HCL-32)、漢密爾頓抑郁量表(HAMD)、修訂版Barratt沖動量表(BIS-11)、修改版外顯行為攻擊量表(MOAS)、蒙特利爾認(rèn)知評價(jià)量表(MoCA)、威斯康星卡片分類測驗(yàn)(WCST)及Stroop測驗(yàn)工具對雙相情感障礙患者進(jìn)行調(diào)查及評估。將所有患者按照修訂版Barratt沖動量表(BIS-11)及修改版外顯行為攻擊量表(MOAS)評分標(biāo)準(zhǔn),分為攻擊組(MOAS加權(quán)總分≥5分,且表中”體力攻擊”項(xiàng)≥1分;BIS-11總分≥70分)33例與非攻擊組(MOAS加權(quán)總分5分且”體力攻擊”項(xiàng)=0分;BIS-11總分70分)39例。結(jié)果:(1)攻擊組與非攻擊組的一般情況經(jīng)比較,差異均無統(tǒng)計(jì)學(xué)意義(P㧐0.05)。(2)攻擊組患者HCL-32得分[18(15,22),P㧐0.05]與非攻擊組患者HCL-32得分[19(16,23)]所表現(xiàn)出的輕躁狂狀態(tài)得分無統(tǒng)計(jì)學(xué)差異性。(3)攻擊組與非攻擊組無論在注意力沖動性、運(yùn)動沖動性還是在無計(jì)劃沖動性上均具有統(tǒng)計(jì)學(xué)意義(P㩳0.05),即攻擊組較非攻擊組在沖動性的三個(gè)維度表現(xiàn)都明顯。(4)攻擊組與非攻擊組WCST測驗(yàn),僅在正確應(yīng)答數(shù)、持續(xù)性應(yīng)答數(shù)及非持續(xù)性錯(cuò)誤數(shù)方面無統(tǒng)計(jì)學(xué)意義(P㧐0.05)。攻擊組表現(xiàn)出更明顯的執(zhí)行功能損害。(5)攻擊組與非攻擊組在Stroop色詞測驗(yàn)測評結(jié)果上未表現(xiàn)出統(tǒng)計(jì)學(xué)差異(P㧐0.05)。攻擊組與非攻擊組在反應(yīng)抑制能力及抗干擾能力上均無明顯差異。(6)攻擊組MoCA總分23.00(20.00,25.00),非攻擊組MoCA總分26.00(23.00,27.00),顯然并不是所有患者都存在認(rèn)知功能的缺損,相比較攻擊組從整體上表現(xiàn)出更明顯的認(rèn)知功能損害。攻擊組與非攻擊組在視空間與執(zhí)行功能、注意、抽象能力及定向力等方面均具有統(tǒng)計(jì)學(xué)差異,(P㩳0.05)。結(jié)論:(1)在整體研究中,伴有沖動攻擊行為的雙相情感障礙患者表現(xiàn)出認(rèn)知功能的損害;而不伴有沖動攻擊行為的雙相情感障礙患者在整體上并未表現(xiàn)出認(rèn)知功能的缺損;(2)從個(gè)體來說,無論是否伴有沖動攻擊行為,雙相情感障礙患者都可能存在認(rèn)知功能損害。(3)有沖動攻擊行為的雙相情感障礙患者相較于無沖動攻擊行為的患者在執(zhí)行功能、注意、抽象能力及定向力等方面表現(xiàn)出更明顯的認(rèn)知功能損害。(4)沖動攻擊行為可以作為預(yù)測雙相情感障礙患者認(rèn)知功能進(jìn)一步損害的獨(dú)立因素。
[Abstract]:Objective: to investigate the characteristics of cognitive impairment in patients with biphasic affective disorder with impulsive aggression, and whether impulsive aggressive behavior in patients with biphasic affective disorder will further aggravate the impairment of cognitive function. It provides a scientific theoretical basis for the prevention and intervention of cognitive impairment. Methods: a cross-section study was conducted in 72 patients with biphasic affective disorder from October 2015 to August 2016 in the Department of Clinical Psychology of Xinjiang Uygur Autonomous region people's Hospital. The scale includes self-designed general situation questionnaire, mild mania symptom scale (HCL-32), Hamilton depression scale (HAMD), revised Barratt impulse scale (BIS-11), modified explicit behavioral attack scale (MOAS),. The Montreal Cognitive rating scale (MoCA),) was used to investigate and evaluate the patients with biphasic affective disorder with the Wisconsin Card sorting Test (WCST) and the Stroop Test. According to the revised Barratt impulse scale (BIS-11) and the modified explicit behavioral attack scale (MOAS), all patients were divided into attack group (MOAS weighted total score 鈮,
本文編號:2482389
[Abstract]:Objective: to investigate the characteristics of cognitive impairment in patients with biphasic affective disorder with impulsive aggression, and whether impulsive aggressive behavior in patients with biphasic affective disorder will further aggravate the impairment of cognitive function. It provides a scientific theoretical basis for the prevention and intervention of cognitive impairment. Methods: a cross-section study was conducted in 72 patients with biphasic affective disorder from October 2015 to August 2016 in the Department of Clinical Psychology of Xinjiang Uygur Autonomous region people's Hospital. The scale includes self-designed general situation questionnaire, mild mania symptom scale (HCL-32), Hamilton depression scale (HAMD), revised Barratt impulse scale (BIS-11), modified explicit behavioral attack scale (MOAS),. The Montreal Cognitive rating scale (MoCA),) was used to investigate and evaluate the patients with biphasic affective disorder with the Wisconsin Card sorting Test (WCST) and the Stroop Test. According to the revised Barratt impulse scale (BIS-11) and the modified explicit behavioral attack scale (MOAS), all patients were divided into attack group (MOAS weighted total score 鈮,
本文編號:2482389
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