【摘要】：目的檢測(cè)正常人房水中與阿爾茨海默病相關(guān)的生物標(biāo)志物——淀粉樣蛋白(β-amyloid protein,Aβ)、Tau蛋白和淀粉樣前體蛋白(amyloid precursor protein,APP)與年齡的相關(guān)性。方法收集116例常規(guī)白內(nèi)障手術(shù)病人房水,按照年齡分為:A組(年齡小于60歲,n=25),B組(年齡60~69歲,n=30),C組(年齡70~79歲,n=32),D組(年齡≥80歲,n=29),運(yùn)用Ellisa方法檢測(cè)樣本中APP、Tau蛋白和Aβ40、Aβ42的濃度。結(jié)果不同年齡組房水中Aβ40、Aβ42、Tau蛋白和APP的濃度差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論正常人房水中Aβ40、Aβ42、Tau蛋白和APP的濃度隨年齡改變沒(méi)有改變。
[Abstract]:Objective to detect the correlation between age and age of 尾 -amyloid protein,A 尾 (尾 -amyloid protein,A 尾) protein and amyloid precursor protein (amyloid precursor protein,APP) in normal aqueous humor. Methods 116 patients with conventional cataract surgery were divided into two groups according to their age: group A (< 60 years old) and group B (age 6069 years) and group C (age 70 ~ 79 years) and group D (age 鈮，

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