發(fā)布時(shí)間：2018-07-02 14:11

  本文選題：心境障礙問(wèn)卷 + 雙相障礙　； 參考：《浙江大學(xué)》2012年碩士論文

【摘要】：背景雙相障礙(bipolar disorder,BPD)具有高發(fā)病率、高自殺致死率、高致殘率的特點(diǎn)。目前臨床存在低診斷率,低正確治療率,流行病學(xué)調(diào)查低發(fā)病率的現(xiàn)象,主要原因是雙相障礙臨床相的復(fù)雜性,診斷標(biāo)準(zhǔn)很難統(tǒng)一。因此,尋找對(duì)BPD具有篩查、診斷價(jià)值的量化指標(biāo)有重要的意義。 目的了解心境障礙問(wèn)卷(MDQ)篩查雙相障礙的價(jià)值,為臨床診斷提供輔助工具。 方法對(duì)48例符合ICD-10抑郁癥診斷標(biāo)準(zhǔn)的住院患者,采用MDQ評(píng)定；以美國(guó)精神障礙診斷與統(tǒng)計(jì)手冊(cè)第四版軸Ⅰ障礙定式檢查-病人研究版(SCID-Ⅰ/P)為標(biāo)準(zhǔn)對(duì)患者進(jìn)行重新診斷,比較兩種方法的結(jié)果。 結(jié)果48例抑郁癥患者中,以MDQ得分≥7分判斷為雙相障礙共13例(27.1%)；SCID-Ⅰ/P診斷為雙相障礙共17例(35.4%),其中MDQ得分≥7分的11例。受試者操作特征曲線(ROC)分析表明,MDQ≥7分篩查雙相障礙的敏感性為0.647,特異性為0.935。采用MDQ篩查與SCID-Ⅰ/診斷的具有較好一致性。以MDQ≥6分作為判斷BPD的陽(yáng)性標(biāo)準(zhǔn),則MDQ從所有17例SCID-Ⅰ/P診斷為BPD患者中篩查出了12例,而31例單相抑郁患者中MQD結(jié)果有29例6分,顯示MDQ評(píng)分≥6分時(shí)篩查雙相障礙的敏感性為0.706,特異性為0.935；而如果以MDQ≥5分為陽(yáng)性結(jié)果,則MDQ從所有17例BPD患者中篩查出了14例,而31例單相抑郁患者中MQD結(jié)果有26例5分,顯示MDQ評(píng)分≥5分時(shí)特異性仍較理想,為0.839,但敏感性提高到了0.824。 結(jié)論住院抑郁癥患者中未被識(shí)別的雙相障礙比例較高, MDQ是一種簡(jiǎn)單、可信的篩查量表,有助于提高臨床醫(yī)生對(duì)雙相障礙的識(shí)別率。僅從臨床篩查目的來(lái)講,以5分為劃界分MDQ篩查BPD更理想。
[Abstract]:Background bipolar disorder (bpd) is characterized by high incidence, high suicide fatality rate and high disability rate. At present, there are low diagnosis rate, low correct treatment rate and low incidence of epidemiology investigation. The main reason is the complexity of the clinical phase of bipolar disorder, and the diagnostic criteria are difficult to unify. Therefore, it is of great significance to search for quantitative indexes with screening and diagnostic value for bpd. Objective to investigate the value of mood disorder questionnaire (MDQ) in the screening of bipolar disorder and to provide an auxiliary tool for clinical diagnosis. Methods Forty-eight inpatients who met the ICD-10 criteria for depression were assessed by MDQ, and the patients were re-diagnosed according to the American Diagnostic and Statistical Manual for Psychiatric Disorder, fourth Edition, Axis 鈪，

本文編號(hào)：2090371