本文選題：糖尿病視網(wǎng)膜病變　切入點：抑郁狀態(tài)　出處：《中國糖尿病雜志》2014年03期 　論文類型：期刊論文

【摘要】：目的評價DR合并抑郁狀態(tài)患者的生命質(zhì)量和人格特征,探討其炎癥因子變化。方法選取新診斷DR(背景期)患者164例,按照抑郁自評量表(SDS)評分分為抑郁狀態(tài)(DRD)組114例和非抑郁狀態(tài)(N-DRD)組50例,采用艾森克人格量表和糖尿病生命質(zhì)量量表評價,檢測生化指標和炎癥因子。結(jié)果 DR合并抑郁狀態(tài)患病率69.51%。與N-DRD組相比,DRD組滿意程度[(36.70±8.38)vs(29.92±8.15)分]、影響程度[(47.51±11.29)vs(39.60±10.37)分]、憂慮程度Ⅰ[(13.56±7.37)vs(8.28±2.39)分]、憂慮程度Ⅱ[(9.23±4.24)vs(5.80±2.22)分]、神經(jīng)質(zhì)[(4.56±3.33)vs(1.84±0.06)分]得分高,內(nèi)外向[(7.98±3.15)vs(9.60±2.65)分]得分低;病程、SBP、FPG、HbA1c、TG、高敏C反應蛋白(hsC-RP)、IL-6、TNF-α、皮質(zhì)醇和胰島素抵抗指數(shù)(HOMA-IR)水平均增高(P均0.05)。SDS評分與hsC-RP、TNF-α呈正相關(guān)。結(jié)論 DR易合并抑郁狀態(tài),且神經(jīng)質(zhì)、內(nèi)向性格、生命質(zhì)量低者更易導致抑郁狀態(tài),hsC-RP和TNF-α是抑郁狀態(tài)的獨立影響因素。
[Abstract]:Objective to evaluate the quality of life (QOL) and personality characteristics in patients with Dr complicated with depression and to explore the changes of inflammatory factors. Methods 164 newly diagnosed patients with DRs (background period) were selected. According to the self-rating depression scale (SDS) score, the patients were divided into two groups: the depression group (n = 114) and the non-depression group (n = 50). Eysenck personality scale and diabetes quality of life scale were used to evaluate the quality of life. Results compared with N-DRD group, the degree of satisfaction [36.70 鹵8.38 vs 29.92 鹵8.15], the degree of influence [47.51 鹵11.29 vs 39.60 鹵10.37], the anxiety degree 鈪，

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