本文選題：焦慮癥　切入點(diǎn)：胃食管返流　出處：《世界華人消化雜志》2014年26期 　論文類型：期刊論文

【摘要】：目的:探究蘭索拉唑聯(lián)合常規(guī)治療方案對焦慮癥患者消化系癥狀治療效果.方法:選取2011-01/2014-03來海南省安寧醫(yī)院就診的焦慮癥合并消化系癥狀患者118例,依據(jù)分層隨機(jī)分組法將患者分為治療組及對照組,每組59例;給予對照組常規(guī)治療方案及消化系癥狀的對癥處理進(jìn)行治療,治療組在對照組治療方案的基礎(chǔ)上給予口服蘭索拉唑片進(jìn)行治療;分別于治療前及治療6 wk后食管pH值(esophageal pH,EpH)、食管下端壓力(lower esophageal sphincter pressure,LESP)、癥狀持續(xù)時間、大便潛血陽性例數(shù)、餐后飽脹、反酸、噯氣及不規(guī)則性腹痛例數(shù)、不良反應(yīng)及藥物不良反應(yīng)情況.結(jié)果:治療前兩組患者的EpH、LESP、大便潛血陽性例數(shù)、餐后飽脹、反酸、噯氣及不規(guī)則性腹痛例數(shù)比較差異無統(tǒng)計學(xué)意義(P0.05);治療6 wk后治療組患者EpH(5.68±1.52)及LESP(12.46 mmHg±4.29 mmHg)明顯高于對照組(4.98±1.47、9.76 mmHg±3.17mmHg),治療組患者癥狀持續(xù)時間、大便潛血陽性例數(shù)、餐后飽脹、反酸、噯氣及不規(guī)則性腹痛例數(shù)明顯低于對照組,差異有統(tǒng)計學(xué)意義(P0.05);治療過程中治療組患者出現(xiàn)持續(xù)性腹痛、腹瀉、貧血及嘔血或便血例數(shù)明顯低于對照組,差異有統(tǒng)計學(xué)意義(P0.05).結(jié)論:聯(lián)合應(yīng)用蘭索拉唑可明顯減輕患者消化系癥狀程度及持續(xù)時間,降低消化系并發(fā)癥進(jìn)展可能.
[Abstract]:Objective: to investigate the therapeutic effect of lansoprazole combined with routine therapy on digestive system symptoms of anxiety patients. Methods: 118 patients with anxiety disorder complicated with digestive system symptoms were selected from 2011-01 / 2014-03 to Hainan Anning Hospital. The patients were divided into treatment group (n = 59) and control group (n = 59). The treatment group was treated with Lansoprazole tablet on the basis of the control group, the esophageal pH value of ephedrine before treatment and 6 weeks after treatment, the lower esophageal pressure lower esophageal sphincter pressureLESPN, the duration of symptoms, and the number of cases with positive occult blood in stool. Postprandial fullness, regurgitation, belching and irregular abdominal pain, adverse reactions and adverse drug reactions. Results: before treatment, the two groups of patients with EpHLESP, stool occult blood positive cases, postprandial fullness, acid regurgitation, There was no significant difference in the number of cases of belching and irregular abdominal pain (P 0.05), EpH(5.68 鹵1.52) and LESP(12.46 mmHg 鹵4.29 mm Hg in the treatment group were significantly higher than those in the control group (4.98 鹵1.47 鹵9.76 mmHg 鹵3.17 mm HgG) after 6 wk treatment. The duration of symptoms, the number of positive cases of stool occult blood, postprandial fullness, acid regurgitation in the treatment group were significantly higher than those in the control group (4.98 鹵1.47 鹵9.76 mmHg 鹵3.17 mm). The number of cases of belching and irregular abdominal pain was significantly lower than that of the control group (P 0.05), and the cases of persistent abdominal pain, diarrhea, anemia and hematemesis or hematochezia in the treatment group were significantly lower than those in the control group. Conclusion: combined use of lansoprazole can significantly reduce the severity and duration of digestive system symptoms and decrease the progression of digestive complications.
【作者單位】： 海南省安寧醫(yī)院精神科;
【分類號】：R749.72

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