【摘要】：目的探討糖尿病酮癥酸中毒（DKA）和高血糖高滲狀態(tài)（HHS）患者相關(guān)的實驗室檢查與病情的關(guān)系。 方法以同濟醫(yī)院1998.01-2010.04收治入院的221位糖尿病酮癥酸中毒患者（包括糖尿病酮癥酸中毒并高血糖高滲狀態(tài)）為研究對象。根據(jù)動脈血氣分析測定結(jié)果分為輕、中、重度三組。回顧性分析221例糖尿病因急性并發(fā)癥入院患者的臨床和實驗資料。 結(jié)果實驗室指標經(jīng)統(tǒng)計學(xué)t檢驗顯示，在DKA和HHS時，，血白細胞計數(shù)、血鉀、血鈉、血肌酐、血淀粉酶、肌酶譜與病情輕重度相關(guān),（P＜0.05），差異均有統(tǒng)計學(xué)意義；紅細胞計數(shù)、紅細胞壓積、血小板計數(shù)、血鈣、血鎂及膽固醇無明顯差別。 結(jié)論在DKA和HHS中除血氣分析是判斷病情輕重的指標外，血白細胞計數(shù)、血鉀、血鈉、血肌酐、血淀粉酶、肌酶譜的升高都是反應(yīng)嚴重性的重要參考。
[Abstract]:Objective to investigate the relationship between laboratory examination and condition of diabetic ketoacidosis (DKA) and hyperglycemia and hyperosmotic (HHS). Methods 221 patients with diabetic ketoacidosis (including diabetic ketoacidosis complicated with hyperglycemia and hyperosmotic status) admitted to Tongji Hospital from August 01 to 20104 were taken as the subjects. According to the results of arterial blood gas analysis, they were divided into three groups: mild, moderate and severe. The clinical and experimental data of 221 patients with diabetes mellitus admitted to hospital due to acute complications were analyzed retrospectively. Results the results of statistical t test showed that there were significant differences in white blood cell count, serum potassium, serum sodium, serum creatinine, serum amylase, muscle zymogram and severity of disease between DKA and HHS, and there was significant difference between the two groups (P < 0.05), and the correlation between blood leukocyte count, serum potassium, sodium, serum creatinine, serum amylase and muscle zymogram was statistically significant (P < 0.05). There were no significant differences in erythrocyte count, hematocrit, platelet count, blood calcium, magnesium and cholesterol. Conclusion in addition to blood gas analysis is an index to judge the severity of the disease in DKA and HHS, the increase of blood white blood cell count, blood potassium, serum sodium, serum creatinine, serum amylase and muscle zymogram are all important references for the severity of the reaction.
【學(xué)位授予單位】：華中科技大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2013
【分類號】：R587.2;R589

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