【摘要】：目的觀察急性心肌梗死(AMI)患者急診經(jīng)皮冠狀動(dòng)脈成形術(shù)(PCI)術(shù)中冠狀動(dòng)脈內(nèi)注射瑞替普酶對(duì)患者的影響。方法 90例AMI患者隨機(jī)分為治療組和對(duì)照組,對(duì)照組直接PCI手術(shù),治療組在冠脈造影結(jié)束后,冠狀動(dòng)脈內(nèi)注射瑞替普酶后行PCI。結(jié)果梗死相關(guān)動(dòng)脈術(shù)后情況比較,對(duì)照組TIMI血流Ⅲ級(jí)發(fā)生率82.2%,治療組TIMI血流Ⅲ級(jí)發(fā)生率97.8%,兩者差異顯著(P0.05),治療組PCI術(shù)后24 h及1 w ST段完全回落均高于對(duì)照組(80%vs 60%;88.9%vs71.1%,P0.05),治療組患者心肌酶和肌鈣蛋白的峰值及PCI術(shù)后1 w數(shù)值均較對(duì)照組低(P0.05)。結(jié)論 AMI患者急診PCI術(shù)中冠狀動(dòng)脈內(nèi)注射瑞替普酶可以更進(jìn)一步再通血管,減輕心肌損傷,保護(hù)心臟,安全有效。
[Abstract]:Objective to observe the effect of intracoronary injection of reteprase during emergency percutaneous transluminal coronary angioplasty (PCI) in patients with acute myocardial infarction (AMI). Methods 90 patients with AMI were randomly divided into treatment group and control group. The control group underwent direct PCI operation. The treatment group received PCI. after coronary arteriography and intracoronary injection of reteprase. Results Infarction related arteries were compared after operation. The incidence of TIMI grade 鈪，

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