【摘要】：目的通過觀察ICU患者輸注不同儲存時間紅細(xì)胞懸液后的臨床效應(yīng),探討適合這類特殊群體輸血的血液要求,為其安全有效輸血提供可靠的循證依據(jù)。方法選取西南醫(yī)科大學(xué)附屬醫(yī)院ICU科,2014年1月1日-2014年12月30日,行紅細(xì)胞輸注治療的符合條件的危重癥患者423例納入此次試驗研究,對其輸血療效和預(yù)后進(jìn)行病例回顧性研究。將納入研究的患者分為2組,分別為輸入平均紅細(xì)胞儲存時間14 d組和輸入平均紅細(xì)胞儲存時間≥14 d組。記錄患者一般情況,入院診斷,ICU期間輸注的RBC總量及次數(shù),ICU期間輸血前后的血紅蛋白濃度,APACHEⅡ評分,機(jī)械通氣時間,器官衰竭情況,ICU停留時間,院內(nèi)感染情況,輸血不良反應(yīng),住院總時間和死亡人數(shù)。統(tǒng)計資料符合正態(tài)分布的選用t檢驗,計數(shù)資料使用卡方檢驗。結(jié)果患者輸血效果與患者APACHEII評分和輸血量,血液儲存時間密切相關(guān),而與其年齡,性別,進(jìn)出ICU的血紅蛋白濃度,機(jī)械通氣時間,ICU停留時間無明顯關(guān)系。患者預(yù)后與血液儲存時間有關(guān),平均庫血時間≥14 d患者和平均庫血時間14 d患者的院內(nèi)感染率分別為6.3%和4.1%,器官衰竭分別為2.8%和1.4%,患者死亡率分別為9.6%和6.5%。結(jié)論輸注紅細(xì)胞平均儲存時間≥14 d的ICU危重患者的院內(nèi)感染率和死亡率,器官衰竭率升高,建議ICU危重患者使用儲存時間14 d的紅細(xì)胞懸液。
[Abstract]:Objective to observe the clinical effect of transfusion of erythrocyte suspension at different storage time in patients with ICU, and to explore the blood requirements suitable for this special group of blood transfusion, and to provide a reliable evidence-based basis for safe and effective blood transfusion. Methods from January 1, 2014 to December 30, 2014, 423 critically ill patients receiving erythrocyte infusion were selected from ICU Department, affiliated Hospital of Southwest Medical University. The curative effect and prognosis of blood transfusion were studied retrospectively. The patients in the study were divided into two groups: the input mean erythrocyte storage time 14 d group and the input average red blood cell storage time 鈮，

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