本文選題：急性心力衰竭 + 尿酸��； 參考：《中國(guó)老年學(xué)雜志》2016年09期

【摘要】：目的探討血清尿酸(UA)對(duì)老年急性心力衰竭患者病情變化的臨床預(yù)測(cè)價(jià)值。方法選取老年急性心力衰竭患者323例。入院后1 h內(nèi)取靜脈血行UA、N末端B型腦利鈉肽前體(NT-pro BNP)、生化、血常規(guī)等檢測(cè),根據(jù)UA水平分組,比較各組患者就診5 d及30 d后隨訪的死亡率,探討UA對(duì)于老年急性心力衰竭患者死亡的預(yù)測(cè)價(jià)值。結(jié)果 (1)應(yīng)用單因素方差分析比較各組患者就診5 d及30 d死亡率,發(fā)現(xiàn)患者5d、30 d死亡率在低UA組與正常UA組間無(wú)顯著差異,而正常UA與高UA組間有顯著差異(9.4%vs 19%,P=0.018;21.3%vs 35%,P=0.010)。(2)應(yīng)用ROC曲線分析UA的評(píng)估價(jià)值:1UA對(duì)于患者就診5 d、30 d死亡率的AUROC分別為0.662和0.588,具有輕度的預(yù)測(cè)價(jià)值;2UA聯(lián)合NTPro BNP對(duì)于急性心力衰竭預(yù)后具有更好的預(yù)測(cè)價(jià)值:UA聯(lián)合NT-pro BNP對(duì)患者就診5 d、30 d死亡率的AUROC分別升至0.701和0.702。結(jié)論雖然UA對(duì)急性心力衰竭的預(yù)后僅有輕度預(yù)測(cè)價(jià)值,但其預(yù)測(cè)價(jià)值與NT-pro BNP相當(dāng);將UA聯(lián)合NT-pro BNP進(jìn)行檢測(cè),可以進(jìn)一步提高NT-pro BNP對(duì)急性心力衰竭患者死亡的預(yù)測(cè)價(jià)值。
[Abstract]:Objective to investigate the clinical predictive value of serum uric acid (UA) in elderly patients with acute heart failure. Methods 323 elderly patients with acute heart failure were selected. The venous blood was collected within 1 hour after admission for the detection of N-terminal B-type brain natriuretic peptide precursor (NT-pro BNP), biochemistry and blood routine. According to the UA level, the mortality of the patients in each group was compared after 5 days and 30 days follow-up. To investigate the predictive value of UA in elderly patients with acute heart failure. Results (1) single factor variance analysis was used to compare the mortality of 5 days and 30 days in all groups. The results showed that there was no significant difference between the low UA group and the normal UA group. There was significant difference between normal UA group and high UA group (9.4%vs 19: P0.018 + 21.3 vs 35g / kg P0.010). (2). The evaluation value of UA by ROC curve analysis was 0.662 and 0.588 for 5 days and 30 days, respectively. There was a slight predictive value of 2UA combined with NTPro BNP for acute heart disease. The prognosis of force failure has a better prognostic value: the AUROC of 30 days death rate in patients treated with NT-pro BNP increased to 0.701 and 0.702 respectively in combination with NT-pro BNP. Conclusion the prognostic value of UA in patients with acute heart failure is only mild, but its predictive value is similar to that of NT-pro BNP, and the detection of UA combined with NT-pro BNP can further improve the predictive value of NT-pro BNP in patients with acute heart failure.
【作者單位】： 首都醫(yī)科大學(xué)宣武醫(yī)院急診科;
【基金】：衛(wèi)生行業(yè)科研專項(xiàng)項(xiàng)目(201002011) 首發(fā)基金項(xiàng)目資助(2009-SHF04)
【分類號(hào)】：R541.6

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 楊萍;老年急性心力衰竭96例臨床分析[J];川北醫(yī)學(xué)院學(xué)報(bào);2004年03期

2 Gheorghiade M. ;Abraham W.T. ;Albert N.M. ;G.C.Fonarow;馬超;;急性心力衰竭住院患者的入院時(shí)收縮壓、臨床特征和預(yù)后[J];世界核心醫(yī)學(xué)期刊文摘(心臟病學(xué)分冊(cè));2007年04期

3 宋金梅;;急性心力衰竭100例救治體會(huì)[J];鄭州大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2007年05期

4 李培杰;楊小華;鄭寧;杜強(qiáng);;2006美歐急性心力衰竭患者院前及早期住院推薦建議簡(jiǎn)讀[J];中國(guó)急救醫(yī)學(xué);2008年06期

5 趙雁薇;王t，

本文編號(hào)：2082191