本文選題：重度燒傷 + 連續(xù)性血液凈化　； 參考：《腎臟病與透析腎移植雜志》2016年01期

【摘要】：目的:觀察連續(xù)性血液凈化(CBP)在重癥燒傷患者救治中的作用。方法:7例大面積重度燒傷患者,合并全身炎癥反應(yīng)綜合征(SIRS)/膿毒癥,和(或)多臟器功能不全綜合征(MODS),在接診24h內(nèi)實(shí)施CBP治療。記錄患者生命體征、血常規(guī)、血生化、肝功能、腎損傷指標(biāo),炎癥指標(biāo)、28d及6個(gè)月死亡率。結(jié)果:7例患者平均燒傷總面積達(dá)91.1%,28d死亡率28.6%(2/7),6個(gè)月死亡率42.9%(3/7)。患者血壓、體溫、炎癥指標(biāo)、血糖、血鈉、尿量等與預(yù)后密切相關(guān)的指標(biāo)相對(duì)穩(wěn)定。結(jié)論:重度燒傷患者及早實(shí)施CBP治療能減輕SIRS/膿毒癥、改善內(nèi)環(huán)境、保護(hù)重要臟器功能和改善預(yù)后。
[Abstract]:Objective: to observe the effect of continuous blood purification (CBP) in the treatment of severe burn patients. Methods Seven patients with large area severe burn were treated with CBP within 24 hours after treatment with systemic inflammatory response syndrome (SIRSN) / sepsis and / or multiple organ dysfunction syndrome (MODS). Vital signs, blood routine examination, blood biochemistry, liver function, renal injury index, inflammation index, 28 days and 6 months mortality were recorded. Results the average total burn area of 7 patients was 91.1 / 28d, the mortality was 28.610 / 7 / 7, and the 6-month mortality was 42.9 / 70.The average burn area of 7 cases was 91.1% / 28d. Blood pressure, body temperature, inflammation, blood glucose, sodium, urine volume and other closely related prognostic indicators are relatively stable. Conclusion: early application of CBP in severe burn patients can alleviate SIRS / sepsis, improve internal environment, protect important organ function and improve prognosis.
【作者單位】： 第二軍醫(yī)大學(xué)金陵醫(yī)院(南京軍區(qū)南京總醫(yī)院)腎臟科;第二軍醫(yī)大學(xué)金陵醫(yī)院(南京軍區(qū)南京總醫(yī)院)國家腎臟疾病臨床醫(yī)學(xué)研究中心全軍腎臟病研究所;
【基金】：國家自然科學(xué)基金面上項(xiàng)目(81170708) 國家科技支撐計(jì)劃課題(2013BAI09B04,2015BAI12B05) 江蘇省臨床醫(yī)學(xué)科技專項(xiàng)(BL2012007)
【分類號(hào)】：R644
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本文編號(hào)：2036125