發(fā)布時(shí)間：2018-06-10 20:01

  本文選題：定植菌 + 病原菌��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年17期

【摘要】：目的探究皮膚去定植菌對(duì)急診危重患者感染的預(yù)防效果。方法選擇2013年1月-2016年12月醫(yī)院急診危重癥患者876例,將患者隨機(jī)分為對(duì)照組和研究組,其中對(duì)照組440例,研究組436例;對(duì)照組患者采用生理鹽水進(jìn)行常規(guī)擦浴,并對(duì)口腔進(jìn)行清潔,研究組患者采用復(fù)方氯己定擦浴、醋酸氯己定溶液對(duì)口腔進(jìn)行清潔,莫匹羅星對(duì)鼻腔進(jìn)行清潔,同時(shí)對(duì)經(jīng)口導(dǎo)管、尿道管及中心靜脈導(dǎo)管用酸性氧化電位水進(jìn)行消毒;對(duì)比兩組患者的感染情況,分析急診危重患者病原菌分布及構(gòu)成比,對(duì)比分析兩組患者血常規(guī)、體溫、C-反應(yīng)蛋白(CRP)、血沉(ESR)及血清降鈣素原(PCT)等指標(biāo)水平。結(jié)果急診危重患者送檢標(biāo)本共檢出563株病原菌,其中革蘭陰性菌286株占50.80%,革蘭陽(yáng)性菌169株占30.02%;真菌108株占19.18%;對(duì)照組患者感染率為4.77%,研究組患者感染率為1.83%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);對(duì)照組患者的白細(xì)胞計(jì)數(shù)、中性粒細(xì)胞計(jì)數(shù)、淋巴細(xì)胞計(jì)數(shù)及單核細(xì)胞數(shù)均高于研究組患者;對(duì)照組患者的體溫、CRP、ESR、PCT、TNF-α、IL-6、IL-8及IL-10水平明顯高于研究組患者,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論皮膚去定植菌能夠降低感染發(fā)生,預(yù)防危重癥患者多藥耐藥菌感染,提高治愈率,減少住院天數(shù)。
[Abstract]:Objective to investigate the preventive effect of dermatogenic bacteria on infection in emergency critical patients. Methods from January 2013 to December 2016, 876 emergency patients were randomly divided into control group (440 cases) and control group (436 cases). The patients in study group were cleaned with compound chlorhexidine, chlorhexidine acetate solution, nasal cavity and transoral catheter. The urethral tube and central venous catheter were disinfected with acid oxidized potential water, the infection of the two groups were compared, the distribution and composition of pathogenic bacteria in the emergency critical patients were analyzed, and the blood routine examination of the two groups were compared. The levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and serum procalcitonin (PCT) were measured. Results A total of 563 strains of pathogenic bacteria were detected in emergency and critical patients. Of these, 286 were Gram-negative bacteria (50.80), 169 Gram-positive bacteria (30.02), 108 fungi (19.18), the control group (4.77) and the study group (1.833). The difference between the two groups was statistically significant (P 0.05). The counts of neutrophils, lymphocytes and monocytes were significantly higher in the control group than in the study group, and the levels of IL-8 and IL-10 in the control group were significantly higher than those in the study group (P 0.05). Conclusion dermatogenic bacteria can reduce the incidence of infection, prevent multidrug resistant bacteria infection in critically ill patients, improve the cure rate and reduce the length of hospitalization.
【作者單位】： 海南醫(yī)學(xué)院附屬第二醫(yī)院東湖院區(qū)急診科;
【分類號(hào)】：R459.7

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