本文選題：缺血性卒中急性期 + 大柴胡湯�。� 參考：《廣西中醫(yī)藥大學》2017年碩士論文

【摘要】：目的:觀察大柴胡湯治療證屬少陽陽明經(jīng)合病的缺血性卒中急性期的臨床療效。方法:本研究納入缺血性卒中急性期證屬少陽陽明合病患者60例,隨機分為對照組與治療組各30例,對照組給予抗血小板藥物、他汀類藥物治療,同時控制血壓、血糖、體溫,予以康復指導。治療組在對照組治療基礎上加用大柴胡湯,連續(xù)治療2周,用神經(jīng)功能缺損評分(NIHSS評分)、日常生活活動能力量表Barthel指數(shù)(BI評分)、實際完成日常生活活動的改良Rankin量表(MRS評分)以及中醫(yī)證候積分、中醫(yī)證候療效進行評價,記錄各組患者治療前后不良反應及評估其安全性,同時通過觀察2組間的數(shù)據(jù)差異對比及統(tǒng)計學分析,進而綜合評測大柴胡湯治療缺血性卒中急性期病屬少陽陽明合病的臨床療效及安全性。結果:(1)臨床療效:治療組總有效率為92.86%,對照組總有效率為71.43%,兩組的總有效率比較具有差異性(P0.05)治療組有效率優(yōu)于對照組。(2)中醫(yī)證候積分:兩組治療前后中醫(yī)證候積分均有顯著差異。組間比較提示治療組與對照組均可顯著改善中醫(yī)證候,但以治療組為優(yōu)。(3)在神經(jīng)功能缺損程度評分(NIHSS)及實際完成日常生活活動的改良Rankin量表(MRS評分)方面,兩組治療前均具有可比性(P0.05),兩組治療后比較,差異均有統(tǒng)計學意義(P0.05),結果顯示治療組優(yōu)于對照組。(4)日常生活活動能力量表Barthel指數(shù)(BI評分):兩組治療前具有可比性(P0.05),兩組治療后比較,具有顯著性差異(P0.05),兩組治療前后差值比較,具有統(tǒng)計學意義(P0.05),治療組優(yōu)于對照組。(5)安全性評價:兩組治療前后的血、尿、糞常規(guī),肝、腎功能,凝血功能及心電圖檢查均無明顯改變,兩組治療前后比較差異均無統(tǒng)計學意義(P0.05)。結論:大柴胡湯能改善證屬少陽陽明經(jīng)合病缺血性卒中急性期患者神經(jīng)功能缺損程度,提高日常生活活動能力。
[Abstract]:Objective: to observe the clinical effect of Dachaihu decoction on acute ischemic stroke with Shaoyang Yangming disease. Methods: sixty patients with acute ischemic stroke were randomly divided into two groups: control group (n = 30) and treatment group (n = 30). The control group was treated with antiplatelet drugs and statins, and the blood pressure, blood glucose and body temperature were controlled at the same time. Give rehabilitation guidance. The treatment group was treated with Dachaihu decoction on the basis of control group for 2 weeks. The neurological deficit score (NIHSS), the activity of daily living (Barthel) index (BI), the modified Rankin scale (Mrs) and the TCM syndromes score were used to evaluate the efficacy of TCM syndromes. Adverse reactions before and after treatment were recorded and their safety was evaluated. Meanwhile, the data differences between the two groups were compared and statistically analyzed. The clinical efficacy and safety of Dachaihu decoction in treating acute ischemic stroke were evaluated. Results: the total effective rate of the treatment group was 92.86, the total effective rate of the control group was 71.43, the total effective rate of the two groups was different (P0.05) the effective rate of the treatment group was better than that of the control group. There are significant differences in integral. The comparison between the two groups indicated that both the treatment group and the control group could significantly improve the TCM syndromes, but the treatment group was the best. The comparison was made between the two groups before and after treatment. The difference was statistically significant (P 0.05). The results showed that the treatment group was superior to the control group (P < 0.05). The Barthel index and BI score of the activity of daily living scale (ADL) were significantly higher in the treatment group than in the control group (P < 0.05). The difference between the two groups was statistically significant (P 0.05). The safety of the treatment group was better than that of the control group (P 0.05): the blood, urine, fecal routine, liver and kidney function of the two groups before and after treatment were evaluated. There were no significant changes in coagulation function and electrocardiogram, and there was no significant difference between the two groups before and after treatment (P 0.05). Conclusion: Dachaihu decoction can improve the degree of nerve function defect and improve the activity of daily living in the patients with acute stroke of Shaoyang Yangming disease.
【學位授予單位】：廣西中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R743.3

【參考文獻】

相關期刊論文 前10條

1 王昊峰;;大柴胡湯加減聯(lián)合西藥治療重癥急性胰腺炎臨床觀察[J];新中醫(yī);2016年10期

2 陳春菊;杜文齊;;大柴胡湯合桃核承氣湯治療慢性哮喘對肺功能及IgE水平的影響[J];四川中醫(yī);2016年06期

3 劉琳;王珩;辛永飛;;大柴胡湯治療腦卒中伴吞咽障礙相關性肺炎臨床療效[J];天津藥學;2016年02期

4 霍曉川;高峰;;中國急性缺血性卒中血管內(nèi)治療現(xiàn)狀初步調(diào)查[J];中國卒中雜志;2016年04期

5 李懷山;劉建云;張穎麗;;補陽還五湯聯(lián)合依達拉奉治療缺血性腦卒中療效及對血液流變學影響[J];中華中醫(yī)藥學刊;2016年03期

6 朱麗娜;陳鄧;陳濤;林燕;徐達;劉凌;;重組組織型纖溶酶原激活物靜脈溶栓治療超時間窗急性缺血性卒中的Meta分析[J];中國現(xiàn)代神經(jīng)疾病雜志;2016年02期

7 蔡小麗;李倩;;益氣活血通絡湯治療缺血性中風臨床研究[J];新中醫(yī);2016年02期

8 王珩;劉琳;辛永飛;王彥云;;大柴胡湯治療卒中相關肺炎臨床觀察[J];天津藥學;2015年06期

9 嚴亞鋒;白海俠;李軍;張學文;;國醫(yī)大師張學文運用川芎藥對經(jīng)驗拾萃[J];世界中西醫(yī)結合雜志;2015年11期

10 馬桂君;李建華;代明志;;中醫(yī)扶陽法在治療中風后遺癥方面的臨床價值探析[J];當代醫(yī)藥論叢;2015年21期

相關重要報紙文章 前1條

1 馮學功;;將大腦按六經(jīng)劃分[N];中國中醫(yī)藥報;2014年

，

本文編號：1928427