重癥醫(yī)學(xué)科導(dǎo)管相關(guān)性血流感染患者流行病學(xué)特點(diǎn)及危險(xiǎn)因素分析
發(fā)布時(shí)間:2018-04-25 23:32
本文選題:重癥醫(yī)學(xué)科 + 導(dǎo)管相關(guān)性血流感染 ; 參考:《中華醫(yī)院感染學(xué)雜志》2017年19期
【摘要】:目的分析重癥醫(yī)學(xué)科導(dǎo)管相關(guān)性血流感染患者流行病學(xué)特點(diǎn)及危險(xiǎn)因素。方法選取2015年4月-2016年4月醫(yī)院重癥監(jiān)護(hù)室473例患者為研究對(duì)象,其中發(fā)生導(dǎo)管相關(guān)性血流相關(guān)感染(CRBSI)患者13例,隨機(jī)選取非CRBSI患者26例為對(duì)照組,研究CRBSI患者流行病學(xué)特點(diǎn)及危險(xiǎn)因素。結(jié)果共有動(dòng)靜脈插管398例,使用率為84.14%,13例發(fā)生CRBSI,感染率為2.75%;其中,兩組患者的死亡數(shù)、平均年齡及糖尿病腎病對(duì)比差異有統(tǒng)計(jì)學(xué)意義(P0.05),而動(dòng)靜脈置管,泌尿道置管等病因?qū)Ρ?差異無(wú)統(tǒng)計(jì)學(xué)意義;兩組空腹血糖升高6.1mmol/L水平,差異無(wú)統(tǒng)計(jì)學(xué)意義;CRBSI患者導(dǎo)管留置時(shí)間(14.24±2.12)d,急性生理與慢性健康評(píng)分(APACHE-Ⅱ)評(píng)分(22.30±5.40)分,CD4~+細(xì)胞(187.00±70.00)個(gè)/μl,體質(zhì)量指數(shù)(BMI)(21.40±3.20)kg/m2,平均動(dòng)脈壓(MAP)(82.10±21.50)mmHg,ICU住院時(shí)間(10.30±2.50)d等指標(biāo)都明顯比非CRBSI患者差,兩組對(duì)比差異有統(tǒng)計(jì)學(xué)意義(P均0.05);導(dǎo)管留置時(shí)間,APACHE評(píng)分,CD4~+細(xì)胞,MAP等進(jìn)行單因素與多因素分析這些指標(biāo)差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論對(duì)重癥醫(yī)學(xué)科導(dǎo)管相關(guān)血流感染患者,提高患者免疫力,縮短留置導(dǎo)管時(shí)間,降低MAP與APACHEⅡ評(píng)分及提升CD4~+細(xì)胞數(shù)量,可有效降低感染率。
[Abstract]:Objective to analyze the epidemiological characteristics and risk factors of catheter-related blood flow infection in severe medical department. Methods from April 2015 to April 2016, 473 patients in intensive care unit of hospital were selected as study subjects, including 13 patients with catheter-associated blood flow related infection, and 26 patients without CRBSI as control group. To study the epidemiological characteristics and risk factors of CRBSI patients. Results there were 398 cases of arteriovenous catheterization, and the rate of CRBSIwas 84.14%, and the infection rate was 2.75. There were significant differences in death, mean age and diabetic nephropathy between the two groups (P 0.05), while the causes of arteriovenous catheterization and urinary tract catheterization were compared. There was no significant difference between the two groups. Fasting blood glucose increased the level of 6.1mmol/L in the two groups. There was no significant difference in catheter indwelling time (14.24 鹵2.12d), acute physiological and chronic health score (APACHE- 鈪,
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