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應(yīng)用磁共振彌散張量成像觀察急性腦梗死患者神經(jīng)纖維束與肢體肌力恢復(fù)的相關(guān)性

發(fā)布時(shí)間:2018-04-25 13:20

  本文選題:卒中 + 腦缺血; 參考:《重慶醫(yī)學(xué)》2017年23期


【摘要】:目的探討磁共振彌散張量成像(DTI)在急性腦梗死患者急性期測(cè)得的各異系數(shù)(FA)值、表現(xiàn)彌散系數(shù)(ADC)值與肢體肌力評(píng)分的相關(guān)性,旨在分析DTI評(píng)價(jià)肢體肌力降低的臨床價(jià)值。方法收集該院2015年6月至2016年6月診斷為急性腦梗死并接受治療的患者20例,對(duì)所有患者在發(fā)病3d內(nèi)測(cè)定簡(jiǎn)化Fugl-Meyer運(yùn)動(dòng)功能評(píng)分并行DTI檢查神經(jīng)纖維束的分布情況,FA值、ADC值的變化。結(jié)果梗死側(cè)FA值、ADC值與健側(cè)對(duì)應(yīng)處比較差異有統(tǒng)計(jì)學(xué)意義(t=-8.70、-18.70,P0.05);梗死側(cè)內(nèi)囊后肢FA值、ADC值與健側(cè)對(duì)應(yīng)處比較差異有統(tǒng)計(jì)學(xué)意義(t=-5.16、-5.08,P0.05);梗死側(cè)內(nèi)囊后肢FA值與簡(jiǎn)化Fugl-Meyer運(yùn)動(dòng)功能評(píng)分呈正相關(guān)(R=0.863,P=0.013)。結(jié)論急性梗死灶與內(nèi)囊后肢的FA值、ADC值均比健側(cè)正常白質(zhì)的FA值、ADC值低,內(nèi)囊后肢的FA值與簡(jiǎn)化Fugl-Meyer運(yùn)動(dòng)功能評(píng)分相關(guān)性較為緊密。
[Abstract]:Objective to investigate the difference coefficient (FA) values measured by magnetic resonance diffusion tensor imaging (DTI) in acute cerebral infarction patients, the correlation of dispersion coefficient (ADC) value and limb muscle strength score, and to analyze the clinical value of DTI to evaluate the reduction of limb muscle strength. Methods the hospital was diagnosed as acute cerebral infarction and accepted from June 2015 to June 2016. 20 patients were treated with a simplified Fugl-Meyer motor function score and DTI examination of the distribution of nerve fibers, FA value, and ADC value in all patients. Results the FA value of the infarct side was statistically significant (t=-8.70, -18.70, P0.05), ADC value and the counterpart of the contralateral side (t=-8.70, -18.70, P0.05); the FA value of the posterior limb of the internal capsule of the infarct, ADC value and the healthy side The corresponding differences were statistically significant (t=-5.16, -5.08, P0.05); the FA value of the posterior limb of the infarct side was positively correlated with the simplified Fugl-Meyer motor function score (R=0.863, P=0.013). Conclusion the FA of the acute infarct and the posterior limb of the internal capsule was lower than the FA value of the normal white matter in the healthy side, the ADC value, the FA value of the posterior limb of the inner capsule and the simplified exercise function. The correlation of score was close.

【作者單位】: 海南省第三人民醫(yī)院神經(jīng)內(nèi)科;海南省第三人民醫(yī)院影像科;
【基金】:海南省衛(wèi)生計(jì)生行業(yè)科研項(xiàng)目(14A200079)
【分類號(hào)】:R743.33
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本文編號(hào):1801514

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