本文選題：急性心肌梗死 + 氯吡格雷��； 參考：《臨床心血管病雜志》2017年07期

【摘要】：目的:評(píng)價(jià)2006-2011年中西部城市地區(qū)急性心肌梗死(AMI)患者住院早期氯吡格雷的使用率及變化情況,并探討影響其使用的因素。方法:采用兩階段隨機(jī)抽樣方法抽取2006年和2011年兩個(gè)年份的AMI患者病歷,提取臨床信息,評(píng)估入院24h內(nèi)氯吡格雷的應(yīng)用情況。采用廣義估計(jì)方程的多水平logistic回歸模型分析影響因素。每年度分別進(jìn)行加權(quán)計(jì)算,以代表中西部城市地區(qū)整體情況。結(jié)果:中西部城市共計(jì)32家醫(yī)院的2 723份AMI病歷納入研究。中位年齡為63歲,女性患者占26.3%。2006-2011年,AMI患者住院早期氯吡格雷使用率從54.2%增加到87.7%(P0.01)。分析早期氯吡格雷使用的影響因素:入院有胸部不適、ST段抬高型心肌梗死、院內(nèi)接受溶栓以及PCI患者更易接受氯吡格雷治療,相反,年齡≥65歲、入院時(shí)收縮壓≥180mmHg(1mmHg=0.133kPa)或舒張壓≥110mmHg患者氯吡格雷使用率低于其他患者。結(jié)論:過(guò)去6年間,我國(guó)中西部城市地區(qū)AMI患者住院早期氯吡格雷應(yīng)用得到顯著改善,但仍然有改善空間。
[Abstract]:Objective: to evaluate the usage and changes of clopidogrel in inpatients with acute myocardial infarction (AMI) in urban areas of central and western China from 2006 to 2011, and to explore the factors affecting the use of clopidogrel.Methods: two stage random sampling method was used to select the medical records of AMI patients in 2006 and 2011, and the clinical information was extracted to evaluate the application of clopidogrel within 24 hours after admission.The multilevel logistic regression model of generalized estimation equation is used to analyze the influencing factors.Each year carries on the weight computation separately, to represent the central and western urban area overall situation.Results: a total of 2 723 AMI cases from 32 hospitals in central and western cities were included in the study.The median age was 63 years, and the percentage of female patients was 26.3%. The utilization rate of clopidogrel increased from 54.2% to 87.7% in early hospitalization of AMI patients from 2006 to 2011.The factors influencing the early use of clopidogrel: patients with chest discomfort and ST-segment elevation myocardial infarction, patients with thrombolytic therapy in hospital and patients with PCI were more likely to receive clopidogrel treatment.The usage rate of clopidogrel in patients with systolic blood pressure 鈮，

本文編號(hào)：1756329