本文選題：腦外傷　切入點：應激反應　出處：《中華醫(yī)院感染學雜志》2017年02期

【摘要】：目的探討全身炎癥反應綜合征修正(ASS)評分、C-反應蛋白及白細胞監(jiān)測鑒別腦外傷患者應激反應與早期感染的臨床價值。方法選取2014年3月-2015年3月收治的腦外傷患者72例,按是否發(fā)生早期感染分為非感染組與感染組,每組36例,兩組患者均在入院1周內(nèi)進行ASS評分,同時分別于入院1、3、5、7、10、14、21d測定患者C-反應蛋白、外周血白細胞計數(shù)(WBC)水平,并記錄其體溫變化。結果感染組ASS評分(8.85±2.37)分,顯著高于非感染組的(4.01±1.22)分,差異有統(tǒng)計學意義(t=3.7738,P0.05),非感染組C-反應蛋白水平無明顯變化;感染組入院1、3、5、7dC-反應蛋白水平顯著高于非感染組,差異有統(tǒng)計學意義(P0.05);感染組入院1、3、5dWBC計數(shù)水平與非感染組接近,但感染組入院7d后WBC水平明顯升高,直至第10天達到峰值,隨后開始逐漸下降,感染組入院1、3、5、7、10、14、21d WBC水平均高于非感染組(P0.05);感染組入院當日均有發(fā)熱癥狀,平均體溫(38.4±1.3)℃,經(jīng)治療后,兩組患者體溫均出現(xiàn)下降,感染組在入院第7天體溫有所升高,直至第10天達到峰值后逐漸下降,與感染組相比,非感染組5d后體溫小幅度變化。結論腦外傷患者入院后的C-反應蛋白、外周血WBC計數(shù)及體溫變化趨勢對早期感染的診斷有指示意義,而ASS評分對早期感染有良好的預測價值,有利于腦外傷早期感染的鑒別診斷。
[Abstract]:Objective to investigate the clinical value of C-reactive protein (CRP) and leukocyte monitoring in differentiating stress reaction from early infection in patients with traumatic brain injury.Methods from March 2014 to March 2015, 72 patients with traumatic brain injury were selected and divided into two groups according to whether early infection occurred. There were 36 cases in each group. The patients in both groups were assessed with ASS within one week of admission.At the same time, the level of C-reactive protein (CRP) and white blood cell count (WBC-) were measured on the 21st day after admission, and their body temperature was recorded.The level of WBC in the infected group was close to that in the non-infected group, but the level of WBC in the infected group increased obviously 7 days after admission, reached its peak value on the 10th day, and then decreased gradually.The WBC level in the infection group was higher than that in the non-infection group on the 21st day after admission, and the fever symptom was found in the infection group on the admission day, the average body temperature was 38.4 鹵1.3 鈩，

本文編號：1692039