發(fā)布時(shí)間：2018-03-26 00:14

  本文選題：血必凈注射液　切入點(diǎn)：膿毒癥　出處：《中國(guó)老年學(xué)雜志》2017年19期

【摘要】：目的探討血必凈注射液對(duì)老年膿毒癥患者心肌損傷的保護(hù)作用。方法選擇老年膿毒癥心肌損傷患者,隨機(jī)分為對(duì)照組和治療組,兩組均給予常規(guī)集束化治療,治療組另外給予血必凈注射液。治療前、治療后5、10 d,抽取靜脈血檢測(cè)肌鈣蛋白I(c Tn I)、肌酸激酶同工酶(CKMB)、降鈣素原(PCT)、C反應(yīng)蛋白(CRP)水平。記錄兩組ICU住院時(shí)間、28 d病死率。結(jié)果治療后5、10 d,兩組c Tn I、CK-MB、PCT、CRP均明顯下降(P0.05),且治療組均明顯低于對(duì)照組(P0.05)。治療組ICU住院時(shí)間明顯短于對(duì)照組(P0.05)。治療組28 d病死率低于對(duì)照組,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論血必凈注射液可以改善老年膿毒癥心肌損傷患者的c Tn I、CK-MB、PCT、CRP水平,對(duì)心肌損傷具有保護(hù)作用。
[Abstract]:Objective to investigate the protective effect of Xuebijing injection on myocardial injury in elderly patients with sepsis. Methods aged patients with sepsis were randomly divided into control group and treatment group. The treatment group was given Xuebijing injection in addition. Before treatment, The levels of cTnTnI, creatine kinase isoenzyme (CKMBN) and procalcitonin (ICU) were measured at 5 and 10 days after treatment. The fatality rate of ICU in both groups was recorded for 28 days. Results after 5 to 10 days of treatment, the levels of CRP in both groups were significantly higher than those in the control group. The ICU hospitalization time of the treatment group was significantly shorter than that of the control group (P 0.05). The fatality rate of the treatment group was lower than that of the control group at 28 days. Conclusion Xuebijing injection can improve the level of CRP in elderly patients with myocardial injury of sepsis and has protective effect on myocardial injury.
【作者單位】： 唐山市第二醫(yī)院ICU;唐山市第二醫(yī)院骨科;唐山市第二醫(yī)院檢驗(yàn)科;唐山市人民醫(yī)院ICU;
【基金】：河北省醫(yī)學(xué)科學(xué)研究重點(diǎn)課題(No.ZD20140379)
【分類號(hào)】：R459.7

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