多發(fā)傷患者CT肺功能成像的臨床應(yīng)用研究
發(fā)布時(shí)間:2018-03-14 16:15
本文選題:多發(fā)傷 切入點(diǎn):肺挫傷 出處:《昆明醫(yī)科大學(xué)》2013年碩士論文 論文類型:學(xué)位論文
【摘要】:目的:探索CT肺功能成像對多發(fā)傷患者肺功能評估的價(jià)值。 方法:收集自2011年1月到2012年12月,創(chuàng)傷后48小時(shí)內(nèi)收住在昆明醫(yī)科大學(xué)第一附屬醫(yī)院的多發(fā)傷患者共61例。AIS-ISS評分10-35分,其中多發(fā)傷(無肺損傷)患者10例為A組,多發(fā)傷(合并肺損傷)患者51例為B組。A組年齡26歲-67歲,平均41.30±12.84歲;B組年齡23歲-70歲,平均41.90±11.54歲。A組體重指數(shù)20.2kg/m2-24.4kg/m2,平均22.92±1.55kg/m2; B組體重指數(shù)20.2kg/m2-25.4kg/m2,平均22.37±1.71kg/m2。兩組間變量均衡性好。所有入選者均在入院當(dāng)天完成CT肺功能成像檢查,即檢查CT肺功能成像中的病變累及范圍(即累及幾個(gè)肺段)為“‘N值”和病變部位的CT值變化為“M值”以及肺功能檢查(PFT)和血?dú)夥治龅软?xiàng)檢查。 結(jié)果:1.對入選患者的AIS-ISS分值、體重指數(shù)和年齡三項(xiàng)基線資料行均衡性分析,標(biāo)準(zhǔn)化差異分別為0.0538、0.05和0.05,均小于0.1,可認(rèn)為組間變量均衡性較好。 2.CT肺功能成像與血?dú)夥治龅臄?shù)據(jù)線性相關(guān)性顯著(r=0.66,F=44.76,P0.01),CT肺功能成像與PFT的數(shù)據(jù)線性相關(guān)性顯著(r=0.68,F=49.88,P0.01),血?dú)夥治龅臄?shù)據(jù)與PFT的數(shù)據(jù)線性相關(guān)性顯著(嚴(yán)0.96F=316.94P0.01) 3.CT肺功能成像“M×N”值與PFT (DLco%)值,比較病例分級結(jié)果,差異無統(tǒng)計(jì)學(xué)意義(x=6.53,P=0.16);以“M×N”值與血?dú)夥治鲋械?Pa02/Fi02)值,比較病例分級結(jié)果,差異無統(tǒng)計(jì)學(xué)意義(x=5.04P=0.28),以PFT (DLco%)值與血?dú)夥治鲋械?Pa02/FiO2)值,比較病例分級結(jié)果,差異有統(tǒng)計(jì)學(xué)意義(x=83.98P0.05) 結(jié)論:1.CT肺功能成像可以評估多發(fā)傷患者的肺功能 2.通過CT肺功能成像,可以對多發(fā)傷患者肺功能進(jìn)行分級
[Abstract]:Objective: to explore the value of CT pulmonary function imaging in evaluating pulmonary function in patients with multiple injury. Methods: from January 2011 to December 2012, 61 patients with multiple injuries admitted to the first affiliated Hospital of Kunming Medical University within 48 hours after trauma were enrolled in this study. AIS-ISS scores were 10-35 points, of which 10 patients with multiple injuries (without lung injury) were selected as group A. 51 patients with multiple injuries (complicated with lung injury) were 26 to 67 years old in group B and group A, with an average age of 41.30 鹵12.84 years and 23 to 70 years old in group B, respectively. The body mass index (BMI) of group A was 20.2kg / m2-24.4kg / m2 (mean 22.92 鹵1.55kg / m2), and that of group B was 20.2kg / m2-25.4 kg / m2 (mean 22.37 鹵1.71kg / m2). There was good balance between the two groups. All the participants completed CT pulmonary function imaging on the day of admission. In other words, the range of lesions involved in CT pulmonary function imaging (that is, several lung segments involved) was "N value", the CT value of lesion site was "M value", the pulmonary function examination was PFTs and blood gas analysis and so on. Results 1. The AIS-ISS score, body mass index and age of the selected patients were analyzed. The standardized differences were 0.0538 / 0. 05 and 0. 05 respectively, which were all less than 0. 1. It could be considered that the equilibrium of variables between groups was better. 2. There is a significant linear correlation between CT pulmonary function imaging and blood gas analysis data. There is a significant linear correlation between CT pulmonary function imaging and PFT data. There is a significant linear correlation between CT pulmonary function imaging and PFT data. The correlation between blood gas analysis data and PFT data is significant (strict 0.96 F 316.94 P 0.01). 3. Ct pulmonary function imaging "M 脳 N" value and PFT "DLCO" value were compared. The difference was not statistically significant (P < 0.05). Using "M 脳 N" value and Pa02 / Fi02 value in blood gas analysis, the difference was not statistically significant between the value of "M 脳 N" and the value of PFT DLCoT (0.28%) and the value of Pa02P / FiO2 in blood gas analysis, and the difference was not statistically significant between the value of "M 脳 N" and the value of "DLCoT" (PFT DLCoT) and the value of Pa02P / FiO2 in blood gas analysis. The difference was statistically significant (83.98 P0.05). Conclusion 1. Ct pulmonary function imaging can be used to evaluate pulmonary function in patients with multiple injuries. 2. Lung function can be graded by CT pulmonary function imaging in patients with multiple injuries.
【學(xué)位授予單位】:昆明醫(yī)科大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2013
【分類號】:R641
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