本文關(guān)鍵詞： 持續(xù)氣道正壓通氣 腦梗死 阻塞性睡眠呼吸暫停綜合征 C反應(yīng)蛋白 白細(xì)胞介素- 白細(xì)胞介素-　出處：《中國老年學(xué)雜志》2017年02期 　論文類型：期刊論文

【摘要】：目的觀察持續(xù)氣道正壓通氣(CPAP)治療后非急性期腦梗死合并阻塞性睡眠呼吸暫停綜合征(OSAHS)患者體內(nèi)炎癥因子的變化。方法 86例非急性期腦梗死合并OSAHS患者,隨機(jī)分為實(shí)驗(yàn)組及對照組。對照組給予常規(guī)腦梗死控制治療。實(shí)驗(yàn)組在常規(guī)腦梗死治療基礎(chǔ)給予CPAP治療,歷時(shí)半年。分別于治療前、治療后1、3、6個(gè)月檢測C反應(yīng)蛋白(CRP)、白細(xì)胞介素(IL)-1、IL-6水平。結(jié)果兩組不同時(shí)段CRP、IL-1、IL-6水平均有顯著差異(P0.05)。結(jié)論 CPAP治療可以控制非急性期腦梗死合并OSAHS患者炎癥反應(yīng)。
[Abstract]:Objective to observe the changes of inflammatory factors in patients with non-acute cerebral infarction complicated with obstructive sleep apnea syndrome (OSAHS) after continuous positive airway pressure ventilation (CPAP). The experimental group was divided into experimental group and control group randomly. The control group was given conventional cerebral infarction control therapy. The experimental group was treated with CPAP on the basis of routine cerebral infarction treatment for half a year. The levels of C-reactive protein (CRP) and interleukin-1 (IL-1) IL-6 were measured at 3 and 6 months after treatment. Results there were significant differences in the levels of IL 6 between the two groups at different time points. Conclusion CPAP treatment can control the inflammatory response of patients with OSAHS in non-acute cerebral infarction.
【作者單位】： 廣東醫(yī)科大學(xué)附屬第二醫(yī)院呼吸內(nèi)科;
【基金】：湛江市財(cái)政資金科技專項(xiàng)競爭性分配項(xiàng)目(No.2013A01017)
【分類號】：R766;R743.33

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本文編號：1498720