2012-2013年上海市普陀區(qū)流感病原學分析
[Abstract]:Objective to understand the epidemiological characteristics of influenza in Putuo district of Shanghai, evaluate the methods of influenza detection and provide scientific basis for the prevention and control of influenza. Methods Nasopharyngeal swabs were collected from influenza surveillance sentinel hospital (Influent Like Illness,ILI in Putuo District Shanghai from January 2012 to December 2013. Real-time fluorescence quantitative PCR was used to detect the nucleic acid of nasopharyngeal swabs. Influenza virus nucleic acid positive samples were isolated and cultured with MDCK cells. Hemagglutination inhibition test (HI) was used to identify the types and subtypes of the isolates. Results from January 2012 to December 2013, a total of 1 707 cases of influenza-like nasopharyngeal swabs were collected, of which 449 were positive for influenza virus nucleic acid, with a total detection rate of 26.30%, of which BV (B-Victoria), BY (B-Yamagata), A H3, A H1N1 accounted for 25.84%, 6.68%, 66.37% and 7.31% of the total positive rate, respectively. The peak period of influenza epidemic in Putuo district of Shanghai was winter and spring. There was significant difference in the positive rate of influenza virus isolation among different age groups (蠂 2, 17.252, P0.001), and the positive rate of influenza virus isolation was the highest in 5-year-old group. There was no significant difference in susceptibility to influenza virus between male and female (蠂 2 = 0.215, P = 0.643), and the sensitivity of influenza B virus isolation and culture on MDCK cells was the best. Conclusion Influenza surveillance should focus on seasonal H3 and A H1N1 epidemics, strengthen the surveillance and control of influenza virus, and the positive rate of influenza virus isolation in 5-year-old group is the highest, especially in primary and secondary schools. The sensitivity of different types of influenza virus in MDCK cell culture needs to be further explored.
【作者單位】: 上海市普陀區(qū)疾病預防控制中心微生物檢驗科;
【分類號】:R511.7
【參考文獻】
相關期刊論文 前4條
1 段蓉;楊質卿;潘引君;;上海市青浦區(qū)2005~2009年流感監(jiān)測結果分析[J];現代預防醫(yī)學;2012年07期
2 朱大方;祖榮強;潘浩;孟繁岳;汪華;;江蘇省2004~2007年流行性感冒監(jiān)測分析[J];中國公共衛(wèi)生;2008年02期
3 黃婷;范軍星;蘇琪茹;劉磊;韓同武;張亞蘭;文艷;金輝;馮奧;許真;周蕾;;城市兒童家庭流感疫苗接種率及接種意愿調查[J];現代預防醫(yī)學;2014年06期
4 劉鳳;;分子技術在流感病毒檢測中的應用[J];現代預防醫(yī)學;2014年12期
【共引文獻】
相關期刊論文 前10條
1 王迎春;王萍;陳葉;;2005-2009年度沈陽市流感監(jiān)測結果分析[J];海峽預防醫(yī)學雜志;2010年06期
2 張惠力;姚杏娟;陳聰;徐輝;;2009-2010年江蘇省常州市流行性感冒監(jiān)測分析[J];疾病監(jiān)測;2011年05期
3 趙志榮;姚為玲;霍開蘭;沈志斌;;安徽省馬鞍山市2006-2007年流感監(jiān)測分析[J];中華疾病控制雜志;2009年02期
4 張洪英;祁賢;潘浩;鄧菲;鄭穎;許文炯;杜雪飛;葉艷華;王燕;石利民;丁潔;謝國祥;;南京市2006年~2009年流行性感冒的病原學檢測分析[J];江蘇預防醫(yī)學;2011年01期
5 孫楠;韓炎;司虹;欒明春;劉丹紅;薄志堅;;2010-2011年大連市哨點醫(yī)院流感監(jiān)測結果分析[J];疾病監(jiān)測與控制;2012年10期
6 陸兵;錢燕華;石平;施超;;2005-2012年無錫市流感流行特征分析[J];中華疾病控制雜志;2013年08期
7 葛愛華;許可;鮑倡俊;余慧燕;鄧斐;秦圓方;朱葉飛;湯奮揚;;流感樣病例和核酸檢測陽性率相關性分析[J];南京醫(yī)科大學學報(自然科學版);2013年12期
8 葛愛華;鮑倡俊;祁賢;朱葉飛;許可;秦圓方;鄧斐;余慧燕;湯奮揚;;江蘇省2009-2012年流感監(jiān)測結果分析[J];中華疾病控制雜志;2014年02期
9 陸瑩;邵慶峰;陳葉;齊英;;沈陽市2011—2012年流感監(jiān)測結果分析[J];海峽預防醫(yī)學雜志;2014年04期
10 常s,
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