發(fā)布時(shí)間：2019-03-08 18:06

【摘要】：目的了解河北省2013-2015年引起急性上呼吸道感染(acute upper respiratory infection,AURI)的病原學(xué)構(gòu)成和流行病學(xué)特征,為呼吸道感染的診斷和防治工作提供科學(xué)依據(jù)。方法采集河北省4家醫(yī)院門(mén)診就診的AURI患者的咽拭子標(biāo)本1 551份,提取核酸后采用多重實(shí)時(shí)熒光定量聚合酶鏈?zhǔn)椒磻?yīng)(polymerase chain reaction,PCR)方法檢測(cè)15種呼吸道病毒。結(jié)果采集1 551份臨床咽拭子標(biāo)本,檢測(cè)出陽(yáng)性標(biāo)本714例,陽(yáng)性率為46.03%,其中鼻病毒陽(yáng)性率最高,為186(11.99%)例,其次為副流感病毒3型167(10.77%)例、呼吸道合胞病毒122(7.87%)例、腺病毒108(6.96%)例、乙型流感病毒56(3.61%)例、人偏肺病毒40(2.58%)例、甲型流感病毒39(2.51%)例、人博卡病毒38(2.45%)例、副流感病毒1型35(2.26%)例、冠狀病毒229E/NL63型33(2.13%)例、腸道病毒32(2.06%)例、副流感病毒4型31(2.00%)例、冠狀病毒OC43型30(1.93%)例、副流感病毒2型11(0.71%)例。病毒混合感染病例176例,檢出率為11.35%。5歲以下年齡組病毒陽(yáng)性率最高為56.07%(337/601)。結(jié)論河北省AURI主要以鼻病毒、副流感病毒3型、呼吸道合胞病毒、腺病毒、流感病毒為主,各病毒有各自的流行特征。
[Abstract]:Objective to investigate the etiology and epidemiological characteristics of acute upper respiratory tract infection (acute upper respiratory infection,AURI) in Hebei Province from 2013 to 2015, and to provide scientific basis for the diagnosis, prevention and treatment of respiratory tract infection. Methods A total of 1 551 pharyngeal swabs were collected from outpatients with AURI from 4 hospitals in Hebei province. 15 respiratory viruses were detected by multiplex real-time fluorescence quantitative polymerase chain reaction (polymerase chain reaction,PCR) after nucleic acid extraction. Results of 1 551 clinical pharyngeal swabs, 714 cases were positive, the positive rate was 46.03%. The highest positive rate of rhinovirus was 186 (11.99%), followed by parainfluenza virus type 3 167 (10.77%), the positive rate of rhinovirus was the highest (11.99%), followed by parainfluenza virus type 3 (10.77%). There were 122 respiratory syncytial viruses (7.87%), 108 adenoviruses (6.96%), 56 influenza B viruses (3.61%), 40 human lung viruses (2.58%) and 39 influenza A viruses (2.51%). There were 38 (2.45%) cases of human Boca virus, 35 (2.26%) of parainfluenza virus, 33 (2.13%) of coronavirus 229E/ NL63, 32 (2.06%) of enterovirus and 31 (2.00%) of parainfluenza virus 4. Coronavirus OC43 30 (1.93%), parainfluenza virus 2 11 (0.71%). In 176 cases of mixed infection, the positive rate was 11.35%. The highest positive rate was 56.07% (337 / 601) in the age group under 5. 5 years old. Conclusion AURI in Hebei Province is mainly rhinovirus, parainfluenza virus type 3, respiratory syncytial virus, adenovirus, influenza virus, and each virus has its own epidemic characteristics.
【作者單位】： 河北省疾病預(yù)防控制中心病毒病防治所;
【基金】：河北省省科技廳項(xiàng)目(13277727D)
【分類(lèi)號(hào)】：R511

【相似文獻(xiàn)】

相關(guān)重要報(bào)紙文章 前7條

1 本報(bào)記者 白軼南 通訊員 黃顯斌;良好衛(wèi)生習(xí)慣 副流感病毒“特效藥”[N];保健時(shí)報(bào);2004年

2 黃顯斌;阻擊副流感病毒　做好預(yù)防是關(guān)鍵[N];中國(guó)婦女報(bào);2004年

3 黃顯斌;傳染病專(zhuān)家指出——對(duì)副流感病毒無(wú)須恐慌[N];中國(guó)中醫(yī)藥報(bào);2004年

4 唐先武 通訊員 黃顯斌;無(wú)須恐慌副流感病毒做好預(yù)防保健是關(guān)鍵[N];科技日?qǐng)?bào);2004年

5 黃顯斌;應(yīng)對(duì)副流感 預(yù)防是關(guān)鍵[N];大眾科技報(bào);2004年

6 任勇;“副流感”不是流感[N];天津日?qǐng)?bào);2004年

7 黃顯斌;傳染病科醫(yī)生說(shuō)：對(duì)副流感無(wú)須恐慌[N];中國(guó)醫(yī)藥報(bào);2004年

，

本文編號(hào)：2437070