【摘要】：目的分析云南省HIV感染者病程長(zhǎng)期不進(jìn)展的影響因素。方法采用1∶1匹配的病例對(duì)照研究方法,以云南省病程長(zhǎng)期(10年)不進(jìn)展的HIV感染者為病例組,病程進(jìn)展的感染者為對(duì)照組,從中國(guó)疾病預(yù)防控制信息系統(tǒng)下載病例資料,并對(duì)感染者進(jìn)行面對(duì)面訪談。使用Epidata3.1建立數(shù)據(jù)庫(kù),并使用SPSS19.0進(jìn)行數(shù)據(jù)處理和統(tǒng)計(jì)分析。結(jié)果病程長(zhǎng)期不進(jìn)展組和病程進(jìn)展組病例數(shù)均為143例。條件Logistic回歸分析顯示,首次CD4+T淋巴細(xì)胞計(jì)數(shù)㧐700個(gè)/μL(OR=5.101,95%CI:1.004~13.819)、隨訪次數(shù)≥20次(OR=26.501,95%CI:2.149~326.847)是HIV感染者病程長(zhǎng)期不進(jìn)展的促進(jìn)因素;注射吸毒感染(OR=0.152,95%CI:0.020~0.381)、未接受社區(qū)美沙酮維持治療(OR=0.005,95%CI:0.001~0.109)是HIV感染者病程進(jìn)展的促進(jìn)因素。結(jié)論 HIV感染者早發(fā)現(xiàn)并保持良好的隨訪依從性能延緩病程發(fā)展,注射吸毒感染且未接受社區(qū)美沙酮維持治療會(huì)促進(jìn)病程發(fā)展。
[Abstract]:Objective to analyze the influencing factors of long-term non-progress of HIV infection in Yunnan province. Methods A 1:1 matched case-control study was used to download the case data from China Disease Prevention and Control Information system (CDIS) with HIV infected persons with long course of disease (10 years) as case group and patients with progressive disease course as control group. The infected persons were interviewed face to face. Use Epidata3.1 to establish database, and use SPSS19.0 for data processing and statistical analysis. Results there were 143 cases in the long-term no progress group and the disease course progress group. Conditional Logistic regression analysis showed that the first CD4 T lymphocyte count of 700 cells per 渭 L (OR=5.101,95%CI:1.004~13.819) and the frequency of follow-up 鈮，

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