中國2015年麻疹風(fēng)疹實(shí)驗(yàn)室網(wǎng)絡(luò)運(yùn)轉(zhuǎn)與評(píng)價(jià)
[Abstract]:Objective to evaluate the operation of measles rubella laboratory network (Measles/rubella laboratory network,MRLN) in China (excluding Hong Kong, Macao Special Administrative region and Taiwan) in 2015. Methods the laboratory data of China measles Surveillance Information report Management system in 2015 and the national MRLN monitoring data were analyzed by descriptive epidemiology method. The indexes of MRLN operation in China were evaluated. Results A total of 104 948 surveillance cases were reported in 2015, of which 42 382 were measles cases, 40 717 (96.07%) were laboratory confirmed cases, 8 143 were rubella cases and 6 324 (77.66%) were laboratory confirmed cases. A total of 400 outbreaks were reported, including 329 measles outbreaks and 31 rubella outbreaks. A total of 90,305 blood samples were collected, and the positive rates of measles and rubella IgM were 38.75 and 6.30 respectively. A total of 45 032 pathogenic specimens were collected from sporadic surveillance cases, and the collection rate was 48. 60%. The positive rate of nucleic acid detection of measles and rubella virus was 35.745.43.29 provincial measles rubella laboratory (Measles/rubella laboratory,MRL), a total of 3,967 measles virus strains were tested, among which 1 strain of Dap9 gene subtype was detected. 16 strains of genotype A (vaccine related strain), 3 950 strains of H1a gene subtype endemic in China, were tested for rubella virus 316 strains with 16 provincial MRL, including 4 strains of genotype 1E and 312 strains of genotype 2B. National MRL and 32 provincial MRL all passed the World Health Organization's functional examination in 2015. Conclusion the MRLN of China in 2015 is working well, which confirms that the epidemic of local measles genotype H1 is still circulating, which provides a good laboratory network support for the elimination of measles in China.
【作者單位】： 中國疾病預(yù)防控制中心病毒病預(yù)防控制所國家衛(wèi)生和計(jì)劃生育委員會(huì)醫(yī)學(xué)病毒學(xué)和病毒病重點(diǎn)實(shí)驗(yàn)室世界衛(wèi)生組織西太平洋區(qū)麻疹參比實(shí)驗(yàn)室;
【基金】：國家自然科學(xué)基金課題(項(xiàng)目號(hào)81371791) 麻疹疾控專項(xiàng)經(jīng)費(fèi)(2015年) 行使WHO西太區(qū)地區(qū)麻疹風(fēng)疹參比實(shí)驗(yàn)室職能(CHN-15-EPI-002033)
【分類號(hào)】：R511
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