【摘要】：目的了解昆明市艾滋病自愿咨詢檢測(VCT)人群中的艾滋病病毒(HIV)的HIV-1亞型和耐藥基因型分布情況。方法于2013年11-12月在云南省疾病預防控制中心VCT門診對就診人群進行調查,并采樣進行HIV抗體、CD4細胞、新發(fā)感染檢測和HIV亞型和耐藥基因型檢測。結果 610例VCT樣本中有96例為HIV抗體陽性(15.7%,96/610),其中95例(99.0%,95/96)獲得亞型分析結果,分別有CRF08_BC(40.0%,38/95)、CRF07_BC(27.4%,26/95)、CRF01_AE(27.4%,26/95)、C(4.2%,4/95)和B(1.1%,1/95)5種亞型。89例樣本(92.7%,89/96)獲得耐藥基因型分析結果,有21例(23.6%,21/89)發(fā)生基因突變,有1例出現耐藥傳播突變位點(1.12%,1/89)。結論 VCT人群中的艾滋病病毒亞型以重組流行型為主,包括CRF08_BC、CRF07_BC和CRF01_AE。耐藥毒株在該人群中為低流行。
[Abstract]:Objective to investigate the distribution of HIV-1 subtypes and drug resistant genotypes of HIV (HIV) in HIV voluntary counseling and detection population in Kunming. Methods from November to December 2013, a survey was carried out in the VCT outpatient clinic of Yunnan Centers for Disease Control and Prevention, and HIV antibody CD4 cells, new infection, HIV subtypes and drug resistant genotypes were detected. 緇撴灉 610渚媀CT鏍鋒湰涓湁96渚嬩負HIV鎶椾綋闃蟲，

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