本文選題：肺結(jié)核 + 肺癌�。� 參考：《中國(guó)現(xiàn)代醫(yī)學(xué)雜志》2015年31期

【摘要】：目的觀察肺結(jié)核并發(fā)肺癌患者的臨床特點(diǎn)和生存狀況,探討影響預(yù)后的相關(guān)因素。方法回顧性分析2004年1月-2009年12月該院收治的80例肺結(jié)核并發(fā)肺癌患者的臨床和影像學(xué)特征。采用Kaplan-Meier法計(jì)算各亞組1、3及5年生存率,并用Log-rank檢驗(yàn)進(jìn)行比較。采用多因素Cox比例風(fēng)險(xiǎn)回歸模型進(jìn)行預(yù)后分析。結(jié)果咳嗽(45.0%)是最常見的首發(fā)癥狀。32例(40.0%)患者的腫瘤位于左肺,39例(48.8)患者的腫瘤位于右肺,9例(11.3%)患者的腫瘤位于雙肺。周圍性肺癌的發(fā)生率為65.0%。最常見的病理類型是鱗癌(57.5%)。腫瘤TNM分期方面,Ⅰ、Ⅱ、Ⅲ及Ⅳ期分別占61.3%、38.8%、27.5%和11.3%。結(jié)節(jié)狀團(tuán)塊是最常見的影像學(xué)表現(xiàn),占41.3%。患者中位生存時(shí)間為27個(gè)月,1、3及5年總生存率分別為66.7%、46.8%和31.1%。肺結(jié)核處于活動(dòng)期、腫瘤TNM分期為Ⅲ~Ⅳ期、結(jié)核與腫瘤病灶不是同一病灶是導(dǎo)致肺結(jié)核并發(fā)肺癌預(yù)后不良的獨(dú)立危險(xiǎn)因素(P0.05)。結(jié)論肺結(jié)核并發(fā)肺癌患者無(wú)特異性的臨床癥狀,影像學(xué)檢查,特別是胸部HRCT有助于早期診斷,肺結(jié)核是否活動(dòng)、腫瘤TNM分期、結(jié)核與腫瘤病灶是否為同一病灶是影響患者預(yù)后的獨(dú)立因素。
[Abstract]:Objective to observe the clinical features and survival status of pulmonary tuberculosis complicated with lung cancer and to explore the related factors affecting prognosis. Methods the clinical and imaging features of 80 patients with pulmonary tuberculosis complicated with lung cancer from January 2004 to December 2009 were retrospectively analyzed. The 3-year and 5-year survival rates of each subgroup were calculated by Kaplan-Meier method and compared with Log-rank test. Multivariate Cox proportional risk regression model was used to analyze the prognosis. Results 45.0) is the most common initial symptom. 32 patients with tumor located in the left lung, 39 patients with tumor located in the right lung, 9 patients with tumor located in the right lung, 11.3) patients with tumor located in both lungs. The incidence of peripheral lung cancer was 65.0. The most common pathological type is squamous cell carcinoma 57.5%. In TNM stage, 鈪，

本文編號(hào)：1958608