醫(yī)院慢性丙型病毒性肝炎患者進展性肝纖維化的發(fā)生率及影響因素研究
發(fā)布時間:2018-05-26 18:00
本文選題:慢性丙型肝炎患者 + 進展性肝纖維化 ; 參考:《中國艾滋病性病》2015年05期
【摘要】:目的了解醫(yī)院慢性丙型病毒性肝炎(簡稱"丙肝")患者的進展性肝纖維化的發(fā)生率和影響因素。方法在北京、河南、吉林、遼寧四個省(直轄市)的4家綜合醫(yī)院中,選取在治的慢性丙肝患者進行問卷調查,內容包括研究對象一般人口學特征、感染途徑、行為學特征、治療情況,并結合病歷收集患者的實驗室檢測等結果。結果共調查慢性丙肝患者359例,其中男性171例(47.6%),女性188例(52.4%),平均年齡(55.1±11.9)歲。有進展性肝纖維化者為218例,發(fā)生率為60.7%。多因素Logistic回歸分析發(fā)現(xiàn),≥40歲、男性、酒精攝入量≥50克/天、未接受抗病毒治療、合并感染艾滋病病毒(HIV)/乙型肝炎病毒(HBV),是影響進展性肝纖維化發(fā)生的5個主要因素。結論醫(yī)院慢性丙肝患者進展性肝纖維化的發(fā)生率較高,應加強丙肝防治知識宣傳,提倡慢性丙肝患者早檢測和早治療,并加強對其飲酒等危險行為的干預,以控制進展性肝纖維化的發(fā)生。
[Abstract]:Objective to investigate the incidence and influencing factors of progressive hepatic fibrosis in patients with chronic viral hepatitis C (HCV) in hospital. Methods in four general hospitals of Beijing, Henan, Jilin and Liaoning provinces (municipalities directly under the Central Government), patients with chronic hepatitis C were investigated by questionnaire, including the general demographic characteristics, infection pathway and behavioral characteristics. Treatment, combined with the patient's medical records collected the results of laboratory tests and so on. Results 359 patients with chronic hepatitis C were investigated, 171 of them were male and 188 were female. The average age was 55. 1 鹵11. 9 years. There were 218 patients with progressive hepatic fibrosis, the incidence was 60.7. Multivariate Logistic regression analysis showed that over 40 years old, male, alcohol intake 鈮,
本文編號:1938303
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