分級接觸者篩查在一起大學生肺結核聚集性發(fā)病調查中的應用
發(fā)布時間:2018-05-02 09:40
本文選題:學生 + 發(fā)病率; 參考:《中國學校衛(wèi)生》2015年05期
【摘要】:目的探討分級接觸者篩查方法在大學生肺結核聚集性發(fā)病調查中的應用效果,為有效控制聚焦性疾病蔓延提供依據(jù)。方法對天津市某大學首發(fā)肺結核病例的接觸者分級篩查,開展流行病學調查、癥狀篩查、PPD試驗、TBSA檢測和胸部DR檢查。結果本次調查逐步篩查了3級接觸者,共934名師生。在1~3級接觸者中,肺結核可疑癥狀發(fā)生率分別為7.1%,0.4%和0.2%,PPD強陽性率分別為62.5%,30.7%和26.7%,TB-SA陽性率分別為45.5%,22.3%和17.4%,DR胸片可疑陰影發(fā)生率分別為16.7%,4.4%和0.6%,各項檢查的陽性率均呈遞減(χ2值分別為36.32,23.02,7.03,52.22,P值均0.05)。最終在接觸者中確診17例學生肺結核病例,從1~3級接觸者的肺結核檢出率分別為14.3%,3.1%和0.6%,差異有統(tǒng)計學意義(χ2=43.97,P0.01)。在宿舍樓層分布上,女生43號樓3層的肺結核罹患率為11.6%,高于男生4層的2.0%及其他樓層的0.8%,差異有統(tǒng)計學意義(χ2=45.97,P0.05);專業(yè)分布上,10級動畫專業(yè)、10級環(huán)藝專業(yè)和其他專業(yè)罹患率分別為18.9%,6.8%和0.6%,差異有統(tǒng)計學意義(χ2=72.30,P0.05)。結論分級接觸者篩查方法適用于學校內結核病疫情調查,可以明確疫情波及人群。調查發(fā)現(xiàn)病例間有流行病學關聯(lián),疫情主要在宿舍樓層及專業(yè)內傳播。
[Abstract]:Objective to explore the effect of the screening method of graded contacts in the investigation of the incidence of pulmonary tuberculosis among college students, and to provide evidence for the effective control of the spread of focused diseases. Methods the first pulmonary tuberculosis cases in a university in Tianjin were screened by grade, epidemiological investigation, PPD test, TBSA test and chest Dr examination were carried out. Results in this survey, 934 teachers and students were gradually screened for level 3 contacts. Among those who are in contact with level 1 or 3, The incidence of suspected symptoms of pulmonary tuberculosis was 7.4% and 0.2%, respectively. The positive rates of PPD were 62.5% and 26.7%, respectively. The positive rates of TB-SA and TB-SA were 45.5% and 17.4%, respectively. The incidence of suspicious shadows in chest radiographs were 16.74.4% and 0.6, respectively. The positive rates of each examination were decreased (蠂 ~ 2 = 36.32, 23.02, 7.032, 7.032, P = 0.05, P = 0.05, respectively). Finally, 17 cases of pulmonary tuberculosis were diagnosed in the contact group. The positive rate of pulmonary tuberculosis from grade 1 to grade 3 was 14. 3% and 0. 6%, respectively. The difference was statistically significant (蠂 2, 43.97, P 0. 01, P < 0. 01, P < 0. 01). In the dormitory floor distribution, The incidence rate of tuberculosis in girls on the third floor of Building 43 was 11.6, which was higher than that of boys on the 4th floor and 0.8% of the other floors (蠂 2 / 45.97 / P0.05), and the incidence rates of students in the 10 ~ (th) level of animation and other majors were 18.998% and 6.8%, respectively. The difference was statistically significant (蠂 2, 72.30, P 0.05). Conclusion the method of graded contact screening is suitable for the investigation of tuberculosis epidemic in schools and can be used to identify the epidemic and the population. The investigation found that there was an epidemiological link between the cases, the epidemic mainly spread within the dormitory floor and professional.
【作者單位】: 天津市結核病控制中心;
【分類號】:R521
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