吉林省2009~2014年麻疹病例含麻疹成分疫苗免疫史對(duì)臨床特征的影響
發(fā)布時(shí)間:2018-04-26 05:00
本文選題:含麻疹成分疫苗 + 免疫史。 參考:《中國疫苗和免疫》2015年04期
【摘要】:目的分析吉林省2009~2014年麻疹病例含麻疹成分疫苗(Measles-containing Vaccine,MCV)免疫史對(duì)臨床特征的影響。方法收集吉林省2009~2014年麻疹監(jiān)測(cè)系統(tǒng)報(bào)告的麻疹確診病例,采用描述流行病學(xué)方法分析年齡及MCV免疫史;選擇實(shí)驗(yàn)室確診麻疹病例,剔除免疫史不詳病例后將病例分為0劑與≥1劑組,運(yùn)用邏輯斯諦(Logistic)回歸分析MCV免疫史對(duì)臨床特征的影響。結(jié)果 Logistic回歸分析結(jié)果顯示,與0劑MCV免疫史麻疹病例相比,≥1劑MCV免疫史麻疹病例發(fā)生咳嗽的比值比(Odds Ratio,OR)為0.514[95%可信區(qū)間(Confidence Interval,CI)為0.369~0.714,P0.05),發(fā)生口腔黏膜斑的OR值為0.451(95%CI:0.386~0.529,P0.05),結(jié)論≥1劑MCV免疫史麻疹病例發(fā)生咳嗽和口腔黏膜斑較0劑MCV免疫史麻疹病例輕,接種MCV對(duì)降低發(fā)病風(fēng)險(xiǎn)、減輕臨床癥狀有重要意義。
[Abstract]:Objective to analyze the effect of the history of measles vaccine measure-containing vaccine MCV on the clinical characteristics of measles cases in Jilin province from 2009 to 2014. Methods the confirmed measles cases reported by the measles Surveillance system from 2009 to 2014 in Jilin Province were collected, the age and MCV immunization history were analyzed by descriptive epidemiology method, and the laboratory confirmed measles cases were selected. The patients were divided into 0 dose group and 鈮,
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