發(fā)布時間：2018-04-04 20:02

  本文選題：夫西地酸乳膏　切入點(diǎn)：細(xì)菌性皮膚感染　出處：《中華醫(yī)院感染學(xué)雜志》2015年02期

【摘要】：目的觀察細(xì)菌性皮膚感染采用夫西地酸乳膏治療的臨床療效和安全性,尋找細(xì)菌性皮膚感染的有效治療方法。方法選取364例細(xì)菌性皮膚感染患者作為研究對象,將患者隨機(jī)分為試驗(yàn)組和對照組,各182例,試驗(yàn)組患者每日外用夫西地酸乳膏涂藥3次,7d為1個療程,滲出性皮損患者先用1∶10 000高錳酸鉀溶液清洗患處后再涂抹藥膏;對照組患者每日外用莫匹羅星軟膏涂抹3次,7d為1個療程,治療前及治療期間不合并使用其他抗菌藥物,對比兩組患者的治療效果。結(jié)果治療后試驗(yàn)組金黃色葡萄球菌、鏈球菌屬、棒桿菌屬及3種菌混合感染患者的清除率分別為83.6%、57.1%、63.6%和60.0%;對照組分別為51.5%、40.7%、33.3%和30.0%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);試驗(yàn)組顯效率為53.3%、總有效率為96.7%,對照組分別為22.5%、75.3%,兩組比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05);試驗(yàn)組有174例患者對夫西地酸乳膏敏感,敏感率為95.6%,對照組132例患者對莫匹羅星軟膏敏感,敏感率為72.5%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論夫西地酸乳膏對細(xì)菌性皮膚感染患者的治療效果良好,且無明顯的不良反應(yīng),同時患者對夫西地酸乳膏的敏感性較高。
[Abstract]:Objective to observe the clinical efficacy and safety of treating bacterial skin infection with Fusidi acid cream, and to find an effective treatment method for bacterial skin infection.Methods 364 patients with bacterial skin infection were randomly divided into experimental group (n = 182) and control group (n = 182).The patients with exudative lesions were first cleaned with potassium permanganate solution at 1:10 before applying ointment, while the patients in the control group were treated with mupiroxine ointment 3 times a day for 7 days as a course of treatment, and no other antibiotics were used before and during the treatment.The therapeutic effects of the two groups were compared.Results after treatment, Staphylococcus aureus and Streptococcus in the experimental group,媯掓潌鑿屽睘鍙，

本文編號：1711466